Diagnóstico médico de depresión se asocia a sospecha de deterioro cognitivo en adultos mayores

Background: Depression has been previously associated with cognitive impairment in high income country populations. However, its association in the Chilean population has not been investigated. Aim: To investigate the association between depression and cognitive impairment. Material and Methods:...

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Autores principales:	Nazar,Gabriela, Ulloa,Natalia, Martínez-Sanguinetti,María Adela, Leiva,Ana María, Petermann-Rocha,Fanny, Martínez,Ximena Díaz, Lanuza,Fabian, Cigarroa,Igor, Concha-Cisternas,Yeny, Troncoso,Claudia, Mardones,Lorena, Villagrán,Marcelo, Celis-Morales,Carlos
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2020
Materias:	Aging Cognitive Dysfunction Depression
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000700947
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spelling	oai:scielo:S0034-988720200007009472020-10-09Diagnóstico médico de depresión se asocia a sospecha de deterioro cognitivo en adultos mayoresNazar,GabrielaUlloa,NataliaMartínez-Sanguinetti,María AdelaLeiva,Ana MaríaPetermann-Rocha,FannyMartínez,Ximena DíazLanuza,FabianCigarroa,IgorConcha-Cisternas,YenyTroncoso,ClaudiaMardones,LorenaVillagrán,MarceloCelis-Morales,Carlos Aging Cognitive Dysfunction Depression Background: Depression has been previously associated with cognitive impairment in high income country populations. However, its association in the Chilean population has not been investigated. Aim: To investigate the association between depression and cognitive impairment. Material and Methods: Data from 1384 Chilean adults aged > 60 years, participating in the National Health Survey 2009-2010 was analyzed. Cognitive impairment was assessed using the Mini Mental Examination score. The medical diagnosis of depression was self-reported. The association between depression and cognitive impairment was assessed using a logistic regression. Results: Depression was positively associated with cognitive impairment. However, the magnitude of the association was higher in men (Odds ratio (OR) = 4.02 [95% confidence intervals (CI): 1.44; 6.61], p < 0.01]) than in women (OR = 2.23 [95%CI: 1.03; 3.43], p = 0.04). Older adults who were diagnosed for the first time with depression after 65 years of age, showed a stronger association with cognitive impairment (OR = 6.65 [95% CI: 2.39; 10.9], p < 0.01) than those diagnosed before 55 years. Conclusions: Our study confirms the association between depression and cognitive impairment. Further research is needed to elucidate the nature and potential mechanisms that link depression with cognitive impairment.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.148 n.7 20202020-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000700947es10.4067/S0034-98872020000700947
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Aging Cognitive Dysfunction Depression
spellingShingle	Aging Cognitive Dysfunction Depression Nazar,Gabriela Ulloa,Natalia Martínez-Sanguinetti,María Adela Leiva,Ana María Petermann-Rocha,Fanny Martínez,Ximena Díaz Lanuza,Fabian Cigarroa,Igor Concha-Cisternas,Yeny Troncoso,Claudia Mardones,Lorena Villagrán,Marcelo Celis-Morales,Carlos Diagnóstico médico de depresión se asocia a sospecha de deterioro cognitivo en adultos mayores
description	Background: Depression has been previously associated with cognitive impairment in high income country populations. However, its association in the Chilean population has not been investigated. Aim: To investigate the association between depression and cognitive impairment. Material and Methods: Data from 1384 Chilean adults aged > 60 years, participating in the National Health Survey 2009-2010 was analyzed. Cognitive impairment was assessed using the Mini Mental Examination score. The medical diagnosis of depression was self-reported. The association between depression and cognitive impairment was assessed using a logistic regression. Results: Depression was positively associated with cognitive impairment. However, the magnitude of the association was higher in men (Odds ratio (OR) = 4.02 [95% confidence intervals (CI): 1.44; 6.61], p < 0.01]) than in women (OR = 2.23 [95%CI: 1.03; 3.43], p = 0.04). Older adults who were diagnosed for the first time with depression after 65 years of age, showed a stronger association with cognitive impairment (OR = 6.65 [95% CI: 2.39; 10.9], p < 0.01) than those diagnosed before 55 years. Conclusions: Our study confirms the association between depression and cognitive impairment. Further research is needed to elucidate the nature and potential mechanisms that link depression with cognitive impairment.
author	Nazar,Gabriela Ulloa,Natalia Martínez-Sanguinetti,María Adela Leiva,Ana María Petermann-Rocha,Fanny Martínez,Ximena Díaz Lanuza,Fabian Cigarroa,Igor Concha-Cisternas,Yeny Troncoso,Claudia Mardones,Lorena Villagrán,Marcelo Celis-Morales,Carlos
author_facet	Nazar,Gabriela Ulloa,Natalia Martínez-Sanguinetti,María Adela Leiva,Ana María Petermann-Rocha,Fanny Martínez,Ximena Díaz Lanuza,Fabian Cigarroa,Igor Concha-Cisternas,Yeny Troncoso,Claudia Mardones,Lorena Villagrán,Marcelo Celis-Morales,Carlos
author_sort	Nazar,Gabriela
title	Diagnóstico médico de depresión se asocia a sospecha de deterioro cognitivo en adultos mayores
title_short	Diagnóstico médico de depresión se asocia a sospecha de deterioro cognitivo en adultos mayores
title_full	Diagnóstico médico de depresión se asocia a sospecha de deterioro cognitivo en adultos mayores
title_fullStr	Diagnóstico médico de depresión se asocia a sospecha de deterioro cognitivo en adultos mayores
title_full_unstemmed	Diagnóstico médico de depresión se asocia a sospecha de deterioro cognitivo en adultos mayores
title_sort	diagnóstico médico de depresión se asocia a sospecha de deterioro cognitivo en adultos mayores
publisher	Sociedad Médica de Santiago
publishDate	2020
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000700947
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Diagnóstico médico de depresión se asocia a sospecha de deterioro cognitivo en adultos mayores

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