Linfoma anaplásico de células grandes asociado a implantes mamarios diagnosticado mediante punción por aguja fina. Caso clínico

Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare type of non-Hodgkin T-cell lymphoma, recently defined in the 2016 World Health Organization (WHO) classification of lymphoid neoplasms. It occurs more commonly when textured implants are used and appears clinically as a la...

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Autores principales: Misad S.,Carlos, Walker B.,Kenneth, Valbuena,José R., Guerra S.,Claudio, Camus A.,Mauricio, Ocqueteau,Mauricio, Loyola,Sandra, Zoroquiain,Pablo
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2020
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000801207
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spelling oai:scielo:S0034-988720200008012072020-12-26Linfoma anaplásico de células grandes asociado a implantes mamarios diagnosticado mediante punción por aguja fina. Caso clínicoMisad S.,CarlosWalker B.,KennethValbuena,José R.Guerra S.,ClaudioCamus A.,MauricioOcqueteau,MauricioLoyola,SandraZoroquiain,Pablo Breast Implants Lymphoma, Non-Hodgkin Pathology, Surgical Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare type of non-Hodgkin T-cell lymphoma, recently defined in the 2016 World Health Organization (WHO) classification of lymphoid neoplasms. It occurs more commonly when textured implants are used and appears clinically as a late seroma. Cytologically, these lesions are composed of large atypical cells with pleomorphic nucleus and an immunophenotype positive for T cell markers and CD30, and negative for ALK1. We report a 56-years-old woman with breast implants who developed a periprosthetic seroma three years after surgery. A fine needle aspiration of the lesion was carried out. Cytology and the immunocytochemical study revealed cells compatible with BIA-ALCL. The flow cytometric study was negative. Excisional biopsy of the capsule was performed, observing that the neoplastic cells were confined to the inner surface of the capsule. Imaging studies did not find evidence of disseminated disease. The present case demonstrates the importance of the study of any late periprosthetic effusion, which can be performed using fine needle aspiration.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.148 n.8 20202020-08-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000801207es10.4067/S0034-98872020000801207
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Breast Implants
Lymphoma, Non-Hodgkin
Pathology, Surgical
spellingShingle Breast Implants
Lymphoma, Non-Hodgkin
Pathology, Surgical
Misad S.,Carlos
Walker B.,Kenneth
Valbuena,José R.
Guerra S.,Claudio
Camus A.,Mauricio
Ocqueteau,Mauricio
Loyola,Sandra
Zoroquiain,Pablo
Linfoma anaplásico de células grandes asociado a implantes mamarios diagnosticado mediante punción por aguja fina. Caso clínico
description Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare type of non-Hodgkin T-cell lymphoma, recently defined in the 2016 World Health Organization (WHO) classification of lymphoid neoplasms. It occurs more commonly when textured implants are used and appears clinically as a late seroma. Cytologically, these lesions are composed of large atypical cells with pleomorphic nucleus and an immunophenotype positive for T cell markers and CD30, and negative for ALK1. We report a 56-years-old woman with breast implants who developed a periprosthetic seroma three years after surgery. A fine needle aspiration of the lesion was carried out. Cytology and the immunocytochemical study revealed cells compatible with BIA-ALCL. The flow cytometric study was negative. Excisional biopsy of the capsule was performed, observing that the neoplastic cells were confined to the inner surface of the capsule. Imaging studies did not find evidence of disseminated disease. The present case demonstrates the importance of the study of any late periprosthetic effusion, which can be performed using fine needle aspiration.
author Misad S.,Carlos
Walker B.,Kenneth
Valbuena,José R.
Guerra S.,Claudio
Camus A.,Mauricio
Ocqueteau,Mauricio
Loyola,Sandra
Zoroquiain,Pablo
author_facet Misad S.,Carlos
Walker B.,Kenneth
Valbuena,José R.
Guerra S.,Claudio
Camus A.,Mauricio
Ocqueteau,Mauricio
Loyola,Sandra
Zoroquiain,Pablo
author_sort Misad S.,Carlos
title Linfoma anaplásico de células grandes asociado a implantes mamarios diagnosticado mediante punción por aguja fina. Caso clínico
title_short Linfoma anaplásico de células grandes asociado a implantes mamarios diagnosticado mediante punción por aguja fina. Caso clínico
title_full Linfoma anaplásico de células grandes asociado a implantes mamarios diagnosticado mediante punción por aguja fina. Caso clínico
title_fullStr Linfoma anaplásico de células grandes asociado a implantes mamarios diagnosticado mediante punción por aguja fina. Caso clínico
title_full_unstemmed Linfoma anaplásico de células grandes asociado a implantes mamarios diagnosticado mediante punción por aguja fina. Caso clínico
title_sort linfoma anaplásico de células grandes asociado a implantes mamarios diagnosticado mediante punción por aguja fina. caso clínico
publisher Sociedad Médica de Santiago
publishDate 2020
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020000801207
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