Síndrome de Cushing provocado por carcinoma suprarrenal gigante. Caso clínico

We report a previously healthy 34-year-old woman, presenting with a seven-month history of arterial hypertension, amenorrhea, weight gain, facial edema, acne, hirsutism and low back pain. A CT scan showed a right adrenal mass of 18 × 13 × 12.5 cm, and multiple vertebral and rib fractures. The hormon...

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Autores principales: Zapata Pizarro,Antonio, Galleguillos Valdivia,Michel, García Jara,Víctor, Espinoza Cohen,Baldo, Ablan Candia,Franklin, Güenchor García,David, Valenzuela Cruz,José
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2020
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020001101679
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spelling oai:scielo:S0034-988720200011016792021-04-04Síndrome de Cushing provocado por carcinoma suprarrenal gigante. Caso clínicoZapata Pizarro,AntonioGalleguillos Valdivia,MichelGarcía Jara,VíctorEspinoza Cohen,BaldoAblan Candia,FranklinGüenchor García,DavidValenzuela Cruz,José Abdominal Neoplasms Adrenal Gland Neoplasms Adrenocortical Hyperfunction Cushing Syndrome We report a previously healthy 34-year-old woman, presenting with a seven-month history of arterial hypertension, amenorrhea, weight gain, facial edema, acne, hirsutism and low back pain. A CT scan showed a right adrenal mass of 18 × 13 × 12.5 cm, and multiple vertebral and rib fractures. The hormonal study confirmed Cushing's Syndrome. Ketoconazole, spironolactone, cotrimoxazole, calcium / vitamin D were started. An adrenalectomy with a right nephrectomy were performed. The excised tumor measured 16 cm and weighed 1.55 kg. There was tumor embolism and a 4 mm soft tissue involvement (pT3NxMx). The right kidney was free of tumor. The patient was treated with chemotherapy (etoposide plus cisplatin). Study of vertebral fractures with magnetic resonance (MRI) showed crush fractures, without images of metastatic bone lesions. One year after surgery, a CT scan showed no signs of tumor recurrence. The patient was lost from follow-up thereafter.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.148 n.11 20202020-11-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020001101679es10.4067/S0034-98872020001101679
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Abdominal Neoplasms
Adrenal Gland Neoplasms
Adrenocortical Hyperfunction
Cushing Syndrome
spellingShingle Abdominal Neoplasms
Adrenal Gland Neoplasms
Adrenocortical Hyperfunction
Cushing Syndrome
Zapata Pizarro,Antonio
Galleguillos Valdivia,Michel
García Jara,Víctor
Espinoza Cohen,Baldo
Ablan Candia,Franklin
Güenchor García,David
Valenzuela Cruz,José
Síndrome de Cushing provocado por carcinoma suprarrenal gigante. Caso clínico
description We report a previously healthy 34-year-old woman, presenting with a seven-month history of arterial hypertension, amenorrhea, weight gain, facial edema, acne, hirsutism and low back pain. A CT scan showed a right adrenal mass of 18 × 13 × 12.5 cm, and multiple vertebral and rib fractures. The hormonal study confirmed Cushing's Syndrome. Ketoconazole, spironolactone, cotrimoxazole, calcium / vitamin D were started. An adrenalectomy with a right nephrectomy were performed. The excised tumor measured 16 cm and weighed 1.55 kg. There was tumor embolism and a 4 mm soft tissue involvement (pT3NxMx). The right kidney was free of tumor. The patient was treated with chemotherapy (etoposide plus cisplatin). Study of vertebral fractures with magnetic resonance (MRI) showed crush fractures, without images of metastatic bone lesions. One year after surgery, a CT scan showed no signs of tumor recurrence. The patient was lost from follow-up thereafter.
author Zapata Pizarro,Antonio
Galleguillos Valdivia,Michel
García Jara,Víctor
Espinoza Cohen,Baldo
Ablan Candia,Franklin
Güenchor García,David
Valenzuela Cruz,José
author_facet Zapata Pizarro,Antonio
Galleguillos Valdivia,Michel
García Jara,Víctor
Espinoza Cohen,Baldo
Ablan Candia,Franklin
Güenchor García,David
Valenzuela Cruz,José
author_sort Zapata Pizarro,Antonio
title Síndrome de Cushing provocado por carcinoma suprarrenal gigante. Caso clínico
title_short Síndrome de Cushing provocado por carcinoma suprarrenal gigante. Caso clínico
title_full Síndrome de Cushing provocado por carcinoma suprarrenal gigante. Caso clínico
title_fullStr Síndrome de Cushing provocado por carcinoma suprarrenal gigante. Caso clínico
title_full_unstemmed Síndrome de Cushing provocado por carcinoma suprarrenal gigante. Caso clínico
title_sort síndrome de cushing provocado por carcinoma suprarrenal gigante. caso clínico
publisher Sociedad Médica de Santiago
publishDate 2020
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020001101679
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