Síndrome de Cushing provocado por carcinoma suprarrenal gigante. Caso clínico
We report a previously healthy 34-year-old woman, presenting with a seven-month history of arterial hypertension, amenorrhea, weight gain, facial edema, acne, hirsutism and low back pain. A CT scan showed a right adrenal mass of 18 × 13 × 12.5 cm, and multiple vertebral and rib fractures. The hormon...
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Sociedad Médica de Santiago
2020
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oai:scielo:S0034-988720200011016792021-04-04Síndrome de Cushing provocado por carcinoma suprarrenal gigante. Caso clínicoZapata Pizarro,AntonioGalleguillos Valdivia,MichelGarcía Jara,VíctorEspinoza Cohen,BaldoAblan Candia,FranklinGüenchor García,DavidValenzuela Cruz,José Abdominal Neoplasms Adrenal Gland Neoplasms Adrenocortical Hyperfunction Cushing Syndrome We report a previously healthy 34-year-old woman, presenting with a seven-month history of arterial hypertension, amenorrhea, weight gain, facial edema, acne, hirsutism and low back pain. A CT scan showed a right adrenal mass of 18 × 13 × 12.5 cm, and multiple vertebral and rib fractures. The hormonal study confirmed Cushing's Syndrome. Ketoconazole, spironolactone, cotrimoxazole, calcium / vitamin D were started. An adrenalectomy with a right nephrectomy were performed. The excised tumor measured 16 cm and weighed 1.55 kg. There was tumor embolism and a 4 mm soft tissue involvement (pT3NxMx). The right kidney was free of tumor. The patient was treated with chemotherapy (etoposide plus cisplatin). Study of vertebral fractures with magnetic resonance (MRI) showed crush fractures, without images of metastatic bone lesions. One year after surgery, a CT scan showed no signs of tumor recurrence. The patient was lost from follow-up thereafter.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.148 n.11 20202020-11-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020001101679es10.4067/S0034-98872020001101679 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
Spanish / Castilian |
topic |
Abdominal Neoplasms Adrenal Gland Neoplasms Adrenocortical Hyperfunction Cushing Syndrome |
spellingShingle |
Abdominal Neoplasms Adrenal Gland Neoplasms Adrenocortical Hyperfunction Cushing Syndrome Zapata Pizarro,Antonio Galleguillos Valdivia,Michel García Jara,Víctor Espinoza Cohen,Baldo Ablan Candia,Franklin Güenchor García,David Valenzuela Cruz,José Síndrome de Cushing provocado por carcinoma suprarrenal gigante. Caso clínico |
description |
We report a previously healthy 34-year-old woman, presenting with a seven-month history of arterial hypertension, amenorrhea, weight gain, facial edema, acne, hirsutism and low back pain. A CT scan showed a right adrenal mass of 18 × 13 × 12.5 cm, and multiple vertebral and rib fractures. The hormonal study confirmed Cushing's Syndrome. Ketoconazole, spironolactone, cotrimoxazole, calcium / vitamin D were started. An adrenalectomy with a right nephrectomy were performed. The excised tumor measured 16 cm and weighed 1.55 kg. There was tumor embolism and a 4 mm soft tissue involvement (pT3NxMx). The right kidney was free of tumor. The patient was treated with chemotherapy (etoposide plus cisplatin). Study of vertebral fractures with magnetic resonance (MRI) showed crush fractures, without images of metastatic bone lesions. One year after surgery, a CT scan showed no signs of tumor recurrence. The patient was lost from follow-up thereafter. |
author |
Zapata Pizarro,Antonio Galleguillos Valdivia,Michel García Jara,Víctor Espinoza Cohen,Baldo Ablan Candia,Franklin Güenchor García,David Valenzuela Cruz,José |
author_facet |
Zapata Pizarro,Antonio Galleguillos Valdivia,Michel García Jara,Víctor Espinoza Cohen,Baldo Ablan Candia,Franklin Güenchor García,David Valenzuela Cruz,José |
author_sort |
Zapata Pizarro,Antonio |
title |
Síndrome de Cushing provocado por carcinoma suprarrenal gigante. Caso clínico |
title_short |
Síndrome de Cushing provocado por carcinoma suprarrenal gigante. Caso clínico |
title_full |
Síndrome de Cushing provocado por carcinoma suprarrenal gigante. Caso clínico |
title_fullStr |
Síndrome de Cushing provocado por carcinoma suprarrenal gigante. Caso clínico |
title_full_unstemmed |
Síndrome de Cushing provocado por carcinoma suprarrenal gigante. Caso clínico |
title_sort |
síndrome de cushing provocado por carcinoma suprarrenal gigante. caso clínico |
publisher |
Sociedad Médica de Santiago |
publishDate |
2020 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872020001101679 |
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