Hipovitaminosis D en población portadora de enfermedad inflamatoria intestinal del Sur de Chile

Background: Inflammatory Bowell Diseases (IBD), either ulcerative colitis (UC) or Chron's disease (CD) are commonly associated with intestinal malabsorption, and insufficient levels 1-25 hydroxycholecalciferol (vitamin D). These insufficient levels could be linked with an increased risk of cli...

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Autores principales:	Horta,Gloria, Soto,Sebastián, Labarca,Gonzalo
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2021
Materias:	Inflammatory Bowel Diseases Vitamin D Vitamin D Deficiency
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872021000300393
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spelling	oai:scielo:S0034-988720210003003932021-10-14Hipovitaminosis D en población portadora de enfermedad inflamatoria intestinal del Sur de ChileHorta,GloriaSoto,SebastiánLabarca,Gonzalo Inflammatory Bowel Diseases Vitamin D Vitamin D Deficiency Background: Inflammatory Bowell Diseases (IBD), either ulcerative colitis (UC) or Chron's disease (CD) are commonly associated with intestinal malabsorption, and insufficient levels 1-25 hydroxycholecalciferol (vitamin D). These insufficient levels could be linked with an increased risk of clinical disease activity. Aim: To report vitamin D levels in patients with IBD living in Southern Chile and their possible association with clinical disease activity. Material and Methods: A prospective, observational study in outpatients with IBD living in Los Angeles, Chile. Demographic data and clinical activity using clinical scores were recorded. Vitamin D levels and fecal calprotectin were measured. Results: We studied 44 patients, 32 (73%) with UC and 12 (27%) with CD. The median age at diagnosis was 33 years old. Forty-one (93%) had mild-inactive disease and 3 (7%) a moderate disease. Mean vitamin D levels were 15.2 ± 7.1 ng/ml. Twenty five percent of patients had sufficient levels (> 20 ng/ml), 35% insufficient levels and 40% poor levels. No association between these levels and disease activity was found. Conclusions: These patients with IBD had a high frequency of hypovitaminosis D.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.149 n.3 20212021-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872021000300393es10.4067/s0034-98872021000300393
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Inflammatory Bowel Diseases Vitamin D Vitamin D Deficiency
spellingShingle	Inflammatory Bowel Diseases Vitamin D Vitamin D Deficiency Horta,Gloria Soto,Sebastián Labarca,Gonzalo Hipovitaminosis D en población portadora de enfermedad inflamatoria intestinal del Sur de Chile
description	Background: Inflammatory Bowell Diseases (IBD), either ulcerative colitis (UC) or Chron's disease (CD) are commonly associated with intestinal malabsorption, and insufficient levels 1-25 hydroxycholecalciferol (vitamin D). These insufficient levels could be linked with an increased risk of clinical disease activity. Aim: To report vitamin D levels in patients with IBD living in Southern Chile and their possible association with clinical disease activity. Material and Methods: A prospective, observational study in outpatients with IBD living in Los Angeles, Chile. Demographic data and clinical activity using clinical scores were recorded. Vitamin D levels and fecal calprotectin were measured. Results: We studied 44 patients, 32 (73%) with UC and 12 (27%) with CD. The median age at diagnosis was 33 years old. Forty-one (93%) had mild-inactive disease and 3 (7%) a moderate disease. Mean vitamin D levels were 15.2 ± 7.1 ng/ml. Twenty five percent of patients had sufficient levels (> 20 ng/ml), 35% insufficient levels and 40% poor levels. No association between these levels and disease activity was found. Conclusions: These patients with IBD had a high frequency of hypovitaminosis D.
author	Horta,Gloria Soto,Sebastián Labarca,Gonzalo
author_facet	Horta,Gloria Soto,Sebastián Labarca,Gonzalo
author_sort	Horta,Gloria
title	Hipovitaminosis D en población portadora de enfermedad inflamatoria intestinal del Sur de Chile
title_short	Hipovitaminosis D en población portadora de enfermedad inflamatoria intestinal del Sur de Chile
title_full	Hipovitaminosis D en población portadora de enfermedad inflamatoria intestinal del Sur de Chile
title_fullStr	Hipovitaminosis D en población portadora de enfermedad inflamatoria intestinal del Sur de Chile
title_full_unstemmed	Hipovitaminosis D en población portadora de enfermedad inflamatoria intestinal del Sur de Chile
title_sort	hipovitaminosis d en población portadora de enfermedad inflamatoria intestinal del sur de chile
publisher	Sociedad Médica de Santiago
publishDate	2021
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872021000300393
work_keys_str_mv	AT hortagloria hipovitaminosisdenpoblacionportadoradeenfermedadinflamatoriaintestinaldelsurdechile AT sotosebastian hipovitaminosisdenpoblacionportadoradeenfermedadinflamatoriaintestinaldelsurdechile AT labarcagonzalo hipovitaminosisdenpoblacionportadoradeenfermedadinflamatoriaintestinaldelsurdechile
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Hipovitaminosis D en población portadora de enfermedad inflamatoria intestinal del Sur de Chile

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