Puesta al día: carcinoma paratiroideo

Parathyroid carcinoma is a rare malignant disease that presents as a sporadic or familial primary hyperparathyroidism (PHP). The latter is associated with some genetic syndromes. It occurs with equal frequency in both sexes, unlike PHP caused by parathyroid adenoma that is more common in women. It s...

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Autores principales:	Barberán,Marcela, Campusano,Claudia, Salman,Patricio, Trejo,Pamela, Silva-Figueroa,Angélica, Rivera,Sandra, Florenzano,Pablo, Velasco,Soledad, Illanes,Francisca, Trincado,Patricio, Canessa,José, Solar,Antonieta, Moreno,Marcela, Eugenin,Daniela, Jiménez,Beatriz, Arroyo,Patricia
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Médica de Santiago 2021
Materias:	Diagnosis Hypercalcemia Hyperparathyroidism Parathyroid Neoplasms
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872021000300399
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id	oai:scielo:S0034-98872021000300399
record_format	dspace
spelling	oai:scielo:S0034-988720210003003992021-10-14Puesta al día: carcinoma paratiroideoBarberán,MarcelaCampusano,ClaudiaSalman,PatricioTrejo,PamelaSilva-Figueroa,AngélicaRivera,SandraFlorenzano,PabloVelasco,SoledadIllanes,FranciscaTrincado,PatricioCanessa,JoséSolar,AntonietaMoreno,MarcelaEugenin,DanielaJiménez,BeatrizArroyo,Patricia Diagnosis Hypercalcemia Hyperparathyroidism Parathyroid Neoplasms Parathyroid carcinoma is a rare malignant disease that presents as a sporadic or familial primary hyperparathyroidism (PHP). The latter is associated with some genetic syndromes. It occurs with equal frequency in both sexes, unlike PHP caused by parathyroid adenoma that is more common in women. It should be suspected in cases of severe hypercalcemia, with high parathyroid hormone levels and a palpable cervical mass. Given the difficulty in distinguishing between parathyroid carcinoma and adenoma prior to the surgery, the diagnosis is often made after parathyroidectomy. The only curative treatment is complete surgical resection with oncologic block resection of the primary tumor to ensure free margins. Adjuvant therapies with chemotherapy or radiation therapy do not modify overall or disease-free survival. Recurrences are common and re-operation of resectable recurrent disease is recommended. The palliative treatment of symptomatic hypercalcemia is crucial in persistent or recurrent disease after surgery since morbidity and mortality are more associated with hypercalcemia than with tumor burden.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.149 n.3 20212021-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872021000300399es10.4067/s0034-98872021000300399
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Diagnosis Hypercalcemia Hyperparathyroidism Parathyroid Neoplasms
spellingShingle	Diagnosis Hypercalcemia Hyperparathyroidism Parathyroid Neoplasms Barberán,Marcela Campusano,Claudia Salman,Patricio Trejo,Pamela Silva-Figueroa,Angélica Rivera,Sandra Florenzano,Pablo Velasco,Soledad Illanes,Francisca Trincado,Patricio Canessa,José Solar,Antonieta Moreno,Marcela Eugenin,Daniela Jiménez,Beatriz Arroyo,Patricia Puesta al día: carcinoma paratiroideo
description	Parathyroid carcinoma is a rare malignant disease that presents as a sporadic or familial primary hyperparathyroidism (PHP). The latter is associated with some genetic syndromes. It occurs with equal frequency in both sexes, unlike PHP caused by parathyroid adenoma that is more common in women. It should be suspected in cases of severe hypercalcemia, with high parathyroid hormone levels and a palpable cervical mass. Given the difficulty in distinguishing between parathyroid carcinoma and adenoma prior to the surgery, the diagnosis is often made after parathyroidectomy. The only curative treatment is complete surgical resection with oncologic block resection of the primary tumor to ensure free margins. Adjuvant therapies with chemotherapy or radiation therapy do not modify overall or disease-free survival. Recurrences are common and re-operation of resectable recurrent disease is recommended. The palliative treatment of symptomatic hypercalcemia is crucial in persistent or recurrent disease after surgery since morbidity and mortality are more associated with hypercalcemia than with tumor burden.
author	Barberán,Marcela Campusano,Claudia Salman,Patricio Trejo,Pamela Silva-Figueroa,Angélica Rivera,Sandra Florenzano,Pablo Velasco,Soledad Illanes,Francisca Trincado,Patricio Canessa,José Solar,Antonieta Moreno,Marcela Eugenin,Daniela Jiménez,Beatriz Arroyo,Patricia
author_facet	Barberán,Marcela Campusano,Claudia Salman,Patricio Trejo,Pamela Silva-Figueroa,Angélica Rivera,Sandra Florenzano,Pablo Velasco,Soledad Illanes,Francisca Trincado,Patricio Canessa,José Solar,Antonieta Moreno,Marcela Eugenin,Daniela Jiménez,Beatriz Arroyo,Patricia
author_sort	Barberán,Marcela
title	Puesta al día: carcinoma paratiroideo
title_short	Puesta al día: carcinoma paratiroideo
title_full	Puesta al día: carcinoma paratiroideo
title_fullStr	Puesta al día: carcinoma paratiroideo
title_full_unstemmed	Puesta al día: carcinoma paratiroideo
title_sort	puesta al día: carcinoma paratiroideo
publisher	Sociedad Médica de Santiago
publishDate	2021
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872021000300399
work_keys_str_mv	AT barberanmarcela puestaaldiacarcinomaparatiroideo AT campusanoclaudia puestaaldiacarcinomaparatiroideo AT salmanpatricio puestaaldiacarcinomaparatiroideo AT trejopamela puestaaldiacarcinomaparatiroideo AT silvafigueroaangelica puestaaldiacarcinomaparatiroideo AT riverasandra puestaaldiacarcinomaparatiroideo AT florenzanopablo puestaaldiacarcinomaparatiroideo AT velascosoledad puestaaldiacarcinomaparatiroideo AT illanesfrancisca puestaaldiacarcinomaparatiroideo AT trincadopatricio puestaaldiacarcinomaparatiroideo AT canessajose puestaaldiacarcinomaparatiroideo AT solarantonieta puestaaldiacarcinomaparatiroideo AT morenomarcela puestaaldiacarcinomaparatiroideo AT eugenindaniela puestaaldiacarcinomaparatiroideo AT jimenezbeatriz puestaaldiacarcinomaparatiroideo AT arroyopatricia puestaaldiacarcinomaparatiroideo
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Puesta al día: carcinoma paratiroideo

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