Evaluación de la función renal en adultos mayores

The evaluation of renal function in older adults is usually carried out with a creatinine clearance or an estimation of glomerular filtration rate using formulas such as Cockcroft-Gault, MDRD or CKD-EPI. The results obtained with these formulas are often regarded as equivalent. However, in adults ol...

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Autores principales: Vega,Jorge, Huidobro E.,Juan Pablo
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2021
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872021000300409
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spelling oai:scielo:S0034-988720210003004092021-10-14Evaluación de la función renal en adultos mayoresVega,JorgeHuidobro E.,Juan Pablo Aged Creatinine Kidney Diseases Glomerular Filtration Rate Renal Insufficiency, Chronic Renal Insufficiency The evaluation of renal function in older adults is usually carried out with a creatinine clearance or an estimation of glomerular filtration rate using formulas such as Cockcroft-Gault, MDRD or CKD-EPI. The results obtained with these formulas are often regarded as equivalent. However, in adults older than 70 years, the Cockcroft-Gault formula frequently underestimates the glomerular filtration rate with respect to reference methods and the MDRD formula overestimates it. CKD-EPI has a more unpredictable behavior. This leads to erroneously classifying patients in the stages of chronic kidney disease (CKD), artificially increasing the prevalence of this condition, overloading health systems and generating emotional disorders in patients mistakenly classified as carriers of CKD. Also, when kidney function is overestimated, CKD patients are prevented from receiving the treatments appropriate for their condition. In recent years, new formulas have been proposed (FAS, BIS) with a greater accuracy to estimate glomerular filtration rate in older adults. This review describes the behavior of these formulas in a significant number of older adults, from various countries, and proposes using those equations with the best performance in older adults.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.149 n.3 20212021-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872021000300409es10.4067/s0034-98872021000300409
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Aged
Creatinine
Kidney Diseases
Glomerular Filtration Rate
Renal Insufficiency, Chronic
Renal Insufficiency
spellingShingle Aged
Creatinine
Kidney Diseases
Glomerular Filtration Rate
Renal Insufficiency, Chronic
Renal Insufficiency
Vega,Jorge
Huidobro E.,Juan Pablo
Evaluación de la función renal en adultos mayores
description The evaluation of renal function in older adults is usually carried out with a creatinine clearance or an estimation of glomerular filtration rate using formulas such as Cockcroft-Gault, MDRD or CKD-EPI. The results obtained with these formulas are often regarded as equivalent. However, in adults older than 70 years, the Cockcroft-Gault formula frequently underestimates the glomerular filtration rate with respect to reference methods and the MDRD formula overestimates it. CKD-EPI has a more unpredictable behavior. This leads to erroneously classifying patients in the stages of chronic kidney disease (CKD), artificially increasing the prevalence of this condition, overloading health systems and generating emotional disorders in patients mistakenly classified as carriers of CKD. Also, when kidney function is overestimated, CKD patients are prevented from receiving the treatments appropriate for their condition. In recent years, new formulas have been proposed (FAS, BIS) with a greater accuracy to estimate glomerular filtration rate in older adults. This review describes the behavior of these formulas in a significant number of older adults, from various countries, and proposes using those equations with the best performance in older adults.
author Vega,Jorge
Huidobro E.,Juan Pablo
author_facet Vega,Jorge
Huidobro E.,Juan Pablo
author_sort Vega,Jorge
title Evaluación de la función renal en adultos mayores
title_short Evaluación de la función renal en adultos mayores
title_full Evaluación de la función renal en adultos mayores
title_fullStr Evaluación de la función renal en adultos mayores
title_full_unstemmed Evaluación de la función renal en adultos mayores
title_sort evaluación de la función renal en adultos mayores
publisher Sociedad Médica de Santiago
publishDate 2021
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872021000300409
work_keys_str_mv AT vegajorge evaluaciondelafuncionrenalenadultosmayores
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