Desafíos en el manejo de la sedación, analgesia y bloqueo neuromuscular en el paciente crítico COVID-19 en Chile

Approximately 5% of COVID-19 patients will have a severe disease requiring invasive or non-invasive mechanical ventilation. In this conditions, sedatives and analgesics are fundamental to promote tolerance, comfort and synchrony with the mechanical ventilator. High and unusual requirements for sedat...

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Autores principales: Muñoz-Pichuante,Daniel, Grandjean,Juan, Olivares,Felipe, León,Patricio, Álvarez,Ignacia
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2021
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872021000400559
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spelling oai:scielo:S0034-988720210004005592021-08-26Desafíos en el manejo de la sedación, analgesia y bloqueo neuromuscular en el paciente crítico COVID-19 en ChileMuñoz-Pichuante,DanielGrandjean,JuanOlivares,FelipeLeón,PatricioÁlvarez,Ignacia Coronavirus Infections Critical Care Deep Sedation Analgesia Neuromuscular Blockade Approximately 5% of COVID-19 patients will have a severe disease requiring invasive or non-invasive mechanical ventilation. In this conditions, sedatives and analgesics are fundamental to promote tolerance, comfort and synchrony with the mechanical ventilator. High and unusual requirements for sedation, analgesics and neuromuscular blockers have been reported in these patients, contributing to prolonged exposure, a high rate of delirium and prolongation of mechanical ventilation. These factors, added to the progressive shortage of these drugs, a high demand for care and less capacity for personalized attention, have created an adverse scenario for their proper and rational use. This paper proposes different pharmacotherapeutic optimization strategies for a rational management of sedation, analgesia and neuromuscular block in critically ill patients with COVID-19, with the therapeutic alternatives available in Chile.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.149 n.4 20212021-04-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872021000400559es10.4067/s0034-98872021000400559
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Coronavirus Infections
Critical Care
Deep Sedation
Analgesia
Neuromuscular Blockade
spellingShingle Coronavirus Infections
Critical Care
Deep Sedation
Analgesia
Neuromuscular Blockade
Muñoz-Pichuante,Daniel
Grandjean,Juan
Olivares,Felipe
León,Patricio
Álvarez,Ignacia
Desafíos en el manejo de la sedación, analgesia y bloqueo neuromuscular en el paciente crítico COVID-19 en Chile
description Approximately 5% of COVID-19 patients will have a severe disease requiring invasive or non-invasive mechanical ventilation. In this conditions, sedatives and analgesics are fundamental to promote tolerance, comfort and synchrony with the mechanical ventilator. High and unusual requirements for sedation, analgesics and neuromuscular blockers have been reported in these patients, contributing to prolonged exposure, a high rate of delirium and prolongation of mechanical ventilation. These factors, added to the progressive shortage of these drugs, a high demand for care and less capacity for personalized attention, have created an adverse scenario for their proper and rational use. This paper proposes different pharmacotherapeutic optimization strategies for a rational management of sedation, analgesia and neuromuscular block in critically ill patients with COVID-19, with the therapeutic alternatives available in Chile.
author Muñoz-Pichuante,Daniel
Grandjean,Juan
Olivares,Felipe
León,Patricio
Álvarez,Ignacia
author_facet Muñoz-Pichuante,Daniel
Grandjean,Juan
Olivares,Felipe
León,Patricio
Álvarez,Ignacia
author_sort Muñoz-Pichuante,Daniel
title Desafíos en el manejo de la sedación, analgesia y bloqueo neuromuscular en el paciente crítico COVID-19 en Chile
title_short Desafíos en el manejo de la sedación, analgesia y bloqueo neuromuscular en el paciente crítico COVID-19 en Chile
title_full Desafíos en el manejo de la sedación, analgesia y bloqueo neuromuscular en el paciente crítico COVID-19 en Chile
title_fullStr Desafíos en el manejo de la sedación, analgesia y bloqueo neuromuscular en el paciente crítico COVID-19 en Chile
title_full_unstemmed Desafíos en el manejo de la sedación, analgesia y bloqueo neuromuscular en el paciente crítico COVID-19 en Chile
title_sort desafíos en el manejo de la sedación, analgesia y bloqueo neuromuscular en el paciente crítico covid-19 en chile
publisher Sociedad Médica de Santiago
publishDate 2021
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872021000400559
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