Encefalopatía subaguda en una paciente con policondritis recidivante. Caso clínico
Relapsing polychondritis (RP) is a rare multisystemic autoimmune disorder characterized by the inflammation and destruction of cartilages, with preference for auricular, nasal and laryngotracheal cartilages. RP may also affect proteoglycan-rich structures, such as, blood vessels, eyes, kidneys, and...
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Sociedad Médica de Santiago
2021
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oai:scielo:S0034-988720210007010852021-11-04Encefalopatía subaguda en una paciente con policondritis recidivante. Caso clínicoVera,ConstanzaMatamala,José ManuelFeuerhake,WalterNeira,OscarVidal,AaronCastillo,José Luis Brain Diseases Leukocytosis Polychondritis, Relapsing Relapsing polychondritis (RP) is a rare multisystemic autoimmune disorder characterized by the inflammation and destruction of cartilages, with preference for auricular, nasal and laryngotracheal cartilages. RP may also affect proteoglycan-rich structures, such as, blood vessels, eyes, kidneys, and heart. The central nervous system (CNS) is involved in less than 3% of patients. We report a 32-year-old female with RP associated with a progressive subacute encephalopathy characterized by behavioral disturbances, auditory and visual hallucinations. The EEG showed generalized slow activity and a mononuclear pleocytosis with increased protein was found in the cerebrospinal fluid. The brain magnetic resonance imaging showed multiple supra and infratentorial nodular inflammatory lesions. After initiating treatment with corticosteroids and cyclophosphamide, a significant improvement in chondritis and neurological status was observed.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.149 n.7 20212021-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872021000701085es10.4067/s0034-98872021000701085 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
Spanish / Castilian |
topic |
Brain Diseases Leukocytosis Polychondritis, Relapsing |
spellingShingle |
Brain Diseases Leukocytosis Polychondritis, Relapsing Vera,Constanza Matamala,José Manuel Feuerhake,Walter Neira,Oscar Vidal,Aaron Castillo,José Luis Encefalopatía subaguda en una paciente con policondritis recidivante. Caso clínico |
description |
Relapsing polychondritis (RP) is a rare multisystemic autoimmune disorder characterized by the inflammation and destruction of cartilages, with preference for auricular, nasal and laryngotracheal cartilages. RP may also affect proteoglycan-rich structures, such as, blood vessels, eyes, kidneys, and heart. The central nervous system (CNS) is involved in less than 3% of patients. We report a 32-year-old female with RP associated with a progressive subacute encephalopathy characterized by behavioral disturbances, auditory and visual hallucinations. The EEG showed generalized slow activity and a mononuclear pleocytosis with increased protein was found in the cerebrospinal fluid. The brain magnetic resonance imaging showed multiple supra and infratentorial nodular inflammatory lesions. After initiating treatment with corticosteroids and cyclophosphamide, a significant improvement in chondritis and neurological status was observed. |
author |
Vera,Constanza Matamala,José Manuel Feuerhake,Walter Neira,Oscar Vidal,Aaron Castillo,José Luis |
author_facet |
Vera,Constanza Matamala,José Manuel Feuerhake,Walter Neira,Oscar Vidal,Aaron Castillo,José Luis |
author_sort |
Vera,Constanza |
title |
Encefalopatía subaguda en una paciente con policondritis recidivante. Caso clínico |
title_short |
Encefalopatía subaguda en una paciente con policondritis recidivante. Caso clínico |
title_full |
Encefalopatía subaguda en una paciente con policondritis recidivante. Caso clínico |
title_fullStr |
Encefalopatía subaguda en una paciente con policondritis recidivante. Caso clínico |
title_full_unstemmed |
Encefalopatía subaguda en una paciente con policondritis recidivante. Caso clínico |
title_sort |
encefalopatía subaguda en una paciente con policondritis recidivante. caso clínico |
publisher |
Sociedad Médica de Santiago |
publishDate |
2021 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872021000701085 |
work_keys_str_mv |
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