Encefalopatía subaguda en una paciente con policondritis recidivante. Caso clínico

Relapsing polychondritis (RP) is a rare multisystemic autoimmune disorder characterized by the inflammation and destruction of cartilages, with preference for auricular, nasal and laryngotracheal cartilages. RP may also affect proteoglycan-rich structures, such as, blood vessels, eyes, kidneys, and...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Vera,Constanza, Matamala,José Manuel, Feuerhake,Walter, Neira,Oscar, Vidal,Aaron, Castillo,José Luis
Lenguaje:Spanish / Castilian
Publicado: Sociedad Médica de Santiago 2021
Materias:
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872021000701085
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:scielo:S0034-98872021000701085
record_format dspace
spelling oai:scielo:S0034-988720210007010852021-11-04Encefalopatía subaguda en una paciente con policondritis recidivante. Caso clínicoVera,ConstanzaMatamala,José ManuelFeuerhake,WalterNeira,OscarVidal,AaronCastillo,José Luis Brain Diseases Leukocytosis Polychondritis, Relapsing Relapsing polychondritis (RP) is a rare multisystemic autoimmune disorder characterized by the inflammation and destruction of cartilages, with preference for auricular, nasal and laryngotracheal cartilages. RP may also affect proteoglycan-rich structures, such as, blood vessels, eyes, kidneys, and heart. The central nervous system (CNS) is involved in less than 3% of patients. We report a 32-year-old female with RP associated with a progressive subacute encephalopathy characterized by behavioral disturbances, auditory and visual hallucinations. The EEG showed generalized slow activity and a mononuclear pleocytosis with increased protein was found in the cerebrospinal fluid. The brain magnetic resonance imaging showed multiple supra and infratentorial nodular inflammatory lesions. After initiating treatment with corticosteroids and cyclophosphamide, a significant improvement in chondritis and neurological status was observed.info:eu-repo/semantics/openAccessSociedad Médica de SantiagoRevista médica de Chile v.149 n.7 20212021-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872021000701085es10.4067/s0034-98872021000701085
institution Scielo Chile
collection Scielo Chile
language Spanish / Castilian
topic Brain Diseases
Leukocytosis
Polychondritis, Relapsing
spellingShingle Brain Diseases
Leukocytosis
Polychondritis, Relapsing
Vera,Constanza
Matamala,José Manuel
Feuerhake,Walter
Neira,Oscar
Vidal,Aaron
Castillo,José Luis
Encefalopatía subaguda en una paciente con policondritis recidivante. Caso clínico
description Relapsing polychondritis (RP) is a rare multisystemic autoimmune disorder characterized by the inflammation and destruction of cartilages, with preference for auricular, nasal and laryngotracheal cartilages. RP may also affect proteoglycan-rich structures, such as, blood vessels, eyes, kidneys, and heart. The central nervous system (CNS) is involved in less than 3% of patients. We report a 32-year-old female with RP associated with a progressive subacute encephalopathy characterized by behavioral disturbances, auditory and visual hallucinations. The EEG showed generalized slow activity and a mononuclear pleocytosis with increased protein was found in the cerebrospinal fluid. The brain magnetic resonance imaging showed multiple supra and infratentorial nodular inflammatory lesions. After initiating treatment with corticosteroids and cyclophosphamide, a significant improvement in chondritis and neurological status was observed.
author Vera,Constanza
Matamala,José Manuel
Feuerhake,Walter
Neira,Oscar
Vidal,Aaron
Castillo,José Luis
author_facet Vera,Constanza
Matamala,José Manuel
Feuerhake,Walter
Neira,Oscar
Vidal,Aaron
Castillo,José Luis
author_sort Vera,Constanza
title Encefalopatía subaguda en una paciente con policondritis recidivante. Caso clínico
title_short Encefalopatía subaguda en una paciente con policondritis recidivante. Caso clínico
title_full Encefalopatía subaguda en una paciente con policondritis recidivante. Caso clínico
title_fullStr Encefalopatía subaguda en una paciente con policondritis recidivante. Caso clínico
title_full_unstemmed Encefalopatía subaguda en una paciente con policondritis recidivante. Caso clínico
title_sort encefalopatía subaguda en una paciente con policondritis recidivante. caso clínico
publisher Sociedad Médica de Santiago
publishDate 2021
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872021000701085
work_keys_str_mv AT veraconstanza encefalopatiasubagudaenunapacienteconpolicondritisrecidivantecasoclinico
AT matamalajosemanuel encefalopatiasubagudaenunapacienteconpolicondritisrecidivantecasoclinico
AT feuerhakewalter encefalopatiasubagudaenunapacienteconpolicondritisrecidivantecasoclinico
AT neiraoscar encefalopatiasubagudaenunapacienteconpolicondritisrecidivantecasoclinico
AT vidalaaron encefalopatiasubagudaenunapacienteconpolicondritisrecidivantecasoclinico
AT castillojoseluis encefalopatiasubagudaenunapacienteconpolicondritisrecidivantecasoclinico
_version_ 1718437217244807168