Electrophoretic pattern of serum proteins in horses with babesiosis

Serum electrophoresis in cellulose acetate strips is a technique commonly used to separate the protein fractions. This technique allows detecting quantitative and qualitative changes in the serum proteins associated with different diseases. The aim of this study was to characterize the changes of th...

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Autores principales: Barrera,R, Carapeto,MV, Habela,MA, Zaragoza,C
Lenguaje:English
Publicado: Facultad de Ciencias Veterinarias, Universidad Austral de Chile 2010
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0301-732X2010000300008
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spelling oai:scielo:S0301-732X20100003000082010-12-15Electrophoretic pattern of serum proteins in horses with babesiosisBarrera,RCarapeto,MVHabela,MAZaragoza,C electrophoresis serum babesiosis horse Serum electrophoresis in cellulose acetate strips is a technique commonly used to separate the protein fractions. This technique allows detecting quantitative and qualitative changes in the serum proteins associated with different diseases. The aim of this study was to characterize the changes of the serum protein fractions produced in horses suffering from babesiosis and to evaluate its application in its diagnosis. Serum total proteins were calculated and the serum electrophoresis from 53 horses was performed. Animals were classified in two groups: Group I (19 healthy horses) and Group II (34 horses suffering from babesiosis). Babesiosis was diagnosed by indirect immunofluorescence antibody assay. Data obtained in the group of sick horses were compared with those from the healthy horses. Median values from total proteins and &#947;-globulins fraction were significantly higher (P < 0.01) than that observed for the control group. In addition, a statistically significant increase was observed (P < 0.05) in the values of &#945;2-globulin subfraction in the sick horses. Results obtained in this study allow concluding that the most significant alteration observed in the serum electrophoretic pattern of horses suffering from babesiosis is the increase of &#945;2-globulin and &#947;-globulin fractions.info:eu-repo/semantics/openAccessFacultad de Ciencias Veterinarias, Universidad Austral de ChileArchivos de medicina veterinaria v.42 n.3 20102010-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0301-732X2010000300008en10.4067/S0301-732X2010000300008
institution Scielo Chile
collection Scielo Chile
language English
topic electrophoresis
serum
babesiosis
horse
spellingShingle electrophoresis
serum
babesiosis
horse
Barrera,R
Carapeto,MV
Habela,MA
Zaragoza,C
Electrophoretic pattern of serum proteins in horses with babesiosis
description Serum electrophoresis in cellulose acetate strips is a technique commonly used to separate the protein fractions. This technique allows detecting quantitative and qualitative changes in the serum proteins associated with different diseases. The aim of this study was to characterize the changes of the serum protein fractions produced in horses suffering from babesiosis and to evaluate its application in its diagnosis. Serum total proteins were calculated and the serum electrophoresis from 53 horses was performed. Animals were classified in two groups: Group I (19 healthy horses) and Group II (34 horses suffering from babesiosis). Babesiosis was diagnosed by indirect immunofluorescence antibody assay. Data obtained in the group of sick horses were compared with those from the healthy horses. Median values from total proteins and &#947;-globulins fraction were significantly higher (P < 0.01) than that observed for the control group. In addition, a statistically significant increase was observed (P < 0.05) in the values of &#945;2-globulin subfraction in the sick horses. Results obtained in this study allow concluding that the most significant alteration observed in the serum electrophoretic pattern of horses suffering from babesiosis is the increase of &#945;2-globulin and &#947;-globulin fractions.
author Barrera,R
Carapeto,MV
Habela,MA
Zaragoza,C
author_facet Barrera,R
Carapeto,MV
Habela,MA
Zaragoza,C
author_sort Barrera,R
title Electrophoretic pattern of serum proteins in horses with babesiosis
title_short Electrophoretic pattern of serum proteins in horses with babesiosis
title_full Electrophoretic pattern of serum proteins in horses with babesiosis
title_fullStr Electrophoretic pattern of serum proteins in horses with babesiosis
title_full_unstemmed Electrophoretic pattern of serum proteins in horses with babesiosis
title_sort electrophoretic pattern of serum proteins in horses with babesiosis
publisher Facultad de Ciencias Veterinarias, Universidad Austral de Chile
publishDate 2010
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0301-732X2010000300008
work_keys_str_mv AT barrerar electrophoreticpatternofserumproteinsinhorseswithbabesiosis
AT carapetomv electrophoreticpatternofserumproteinsinhorseswithbabesiosis
AT habelama electrophoreticpatternofserumproteinsinhorseswithbabesiosis
AT zaragozac electrophoreticpatternofserumproteinsinhorseswithbabesiosis
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