In vitro bactericidal activity of equine platelet concentrates, platelet poor plasma, and plasma against methicillin-resistant Staphylococcus aureus
The aims of the study were 1) to evaluate the antibacterial effect of equine platelet concentrates (ePCs) (either activated or not with calcium gluconate (CG)) against methicillin-resistant Staphylococcus aureus (MRSA), and 2) to compare their antibacterial effect with activated platelet poor plasma...
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| Lenguaje: | English |
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Facultad de Ciencias Veterinarias, Universidad Austral de Chile
2011
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oai:scielo:S0301-732X20110002000082011-11-17In vitro bactericidal activity of equine platelet concentrates, platelet poor plasma, and plasma against methicillin-resistant Staphylococcus aureusÁlvarez,MELópez,CGiraldo,CESamudio,ICarmona,JU equine platelet rich plasma antimicrobial effect infection Staphylococcus aureus The aims of the study were 1) to evaluate the antibacterial effect of equine platelet concentrates (ePCs) (either activated or not with calcium gluconate (CG)) against methicillin-resistant Staphylococcus aureus (MRSA), and 2) to compare their antibacterial effect with activated platelet poor plasma (PPP) and plasma (P). Blood products were allotted in 4 groups (ePC, ePC/CG, PPP/CG, and P) plus a positive control group (PCG) and a negative control group, and mixed with MRSA and Mueller-Hinton broth. Samples were incubated during 1, 4, 8, 12, and 24 h, and colony-forming units were counted. The bacterial growth was significantly (P = 0.01) inhibited by the ePC, ePC/CG, PPP/CG and P in comparison with the PCG during the first 12 h. At 24h only a statistically significant (P = 0.01) antibacterial effect was noticed for the ePC, ePC/ CG and PPP/CG in comparison with the PCG and P. Equine PCs and PPP provided the best in vitro antibacterial effect against MRSA.info:eu-repo/semantics/openAccessFacultad de Ciencias Veterinarias, Universidad Austral de ChileArchivos de medicina veterinaria v.43 n.2 20112011-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0301-732X2011000200008en10.4067/S0301-732X2011000200008 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
English |
| topic |
equine platelet rich plasma antimicrobial effect infection Staphylococcus aureus |
| spellingShingle |
equine platelet rich plasma antimicrobial effect infection Staphylococcus aureus Álvarez,ME López,C Giraldo,CE Samudio,I Carmona,JU In vitro bactericidal activity of equine platelet concentrates, platelet poor plasma, and plasma against methicillin-resistant Staphylococcus aureus |
| description |
The aims of the study were 1) to evaluate the antibacterial effect of equine platelet concentrates (ePCs) (either activated or not with calcium gluconate (CG)) against methicillin-resistant Staphylococcus aureus (MRSA), and 2) to compare their antibacterial effect with activated platelet poor plasma (PPP) and plasma (P). Blood products were allotted in 4 groups (ePC, ePC/CG, PPP/CG, and P) plus a positive control group (PCG) and a negative control group, and mixed with MRSA and Mueller-Hinton broth. Samples were incubated during 1, 4, 8, 12, and 24 h, and colony-forming units were counted. The bacterial growth was significantly (P = 0.01) inhibited by the ePC, ePC/CG, PPP/CG and P in comparison with the PCG during the first 12 h. At 24h only a statistically significant (P = 0.01) antibacterial effect was noticed for the ePC, ePC/ CG and PPP/CG in comparison with the PCG and P. Equine PCs and PPP provided the best in vitro antibacterial effect against MRSA. |
| author |
Álvarez,ME López,C Giraldo,CE Samudio,I Carmona,JU |
| author_facet |
Álvarez,ME López,C Giraldo,CE Samudio,I Carmona,JU |
| author_sort |
Álvarez,ME |
| title |
In vitro bactericidal activity of equine platelet concentrates, platelet poor plasma, and plasma against methicillin-resistant Staphylococcus aureus |
| title_short |
In vitro bactericidal activity of equine platelet concentrates, platelet poor plasma, and plasma against methicillin-resistant Staphylococcus aureus |
| title_full |
In vitro bactericidal activity of equine platelet concentrates, platelet poor plasma, and plasma against methicillin-resistant Staphylococcus aureus |
| title_fullStr |
In vitro bactericidal activity of equine platelet concentrates, platelet poor plasma, and plasma against methicillin-resistant Staphylococcus aureus |
| title_full_unstemmed |
In vitro bactericidal activity of equine platelet concentrates, platelet poor plasma, and plasma against methicillin-resistant Staphylococcus aureus |
| title_sort |
in vitro bactericidal activity of equine platelet concentrates, platelet poor plasma, and plasma against methicillin-resistant staphylococcus aureus |
| publisher |
Facultad de Ciencias Veterinarias, Universidad Austral de Chile |
| publishDate |
2011 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0301-732X2011000200008 |
| work_keys_str_mv |
AT alvarezme invitrobactericidalactivityofequineplateletconcentratesplateletpoorplasmaandplasmaagainstmethicillinresistantstaphylococcusaureus AT lopezc invitrobactericidalactivityofequineplateletconcentratesplateletpoorplasmaandplasmaagainstmethicillinresistantstaphylococcusaureus AT giraldoce invitrobactericidalactivityofequineplateletconcentratesplateletpoorplasmaandplasmaagainstmethicillinresistantstaphylococcusaureus AT samudioi invitrobactericidalactivityofequineplateletconcentratesplateletpoorplasmaandplasmaagainstmethicillinresistantstaphylococcusaureus AT carmonaju invitrobactericidalactivityofequineplateletconcentratesplateletpoorplasmaandplasmaagainstmethicillinresistantstaphylococcusaureus |
| _version_ |
1718437895384072192 |