Autologous implant of bone marrow mononuclear stem-cells as treatment for equine bicipital tendonitis: case report

Bicipital bursitis in the horse, the inflammation of the bicipital tendon and its surrounding bursa, has been reported to represent a low percentage of lameness cause. However, it is the main cause of lameness associated to the shoulder region and it has been under diagnosed. Due to high recurrence...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Menarim,BC, Fortini,GA, Álvarez,PS, Gómez,J, Jarrín,CD, Ramírez,A, Galecio,JS
Lenguaje:	English
Publicado:	Facultad de Ciencias Veterinarias, Universidad Austral de Chile 2012
Materias:	tendon injuries cell therapy horses shoulder lameness
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0301-732X2012000300013
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0301-732X2012000300013
record_format	dspace
spelling	oai:scielo:S0301-732X20120003000132013-01-28Autologous implant of bone marrow mononuclear stem-cells as treatment for equine bicipital tendonitis: case reportMenarim,BCFortini,GAÁlvarez,PSGómez,JJarrín,CDRamírez,AGalecio,JS tendon injuries cell therapy horses shoulder lameness Bicipital bursitis in the horse, the inflammation of the bicipital tendon and its surrounding bursa, has been reported to represent a low percentage of lameness cause. However, it is the main cause of lameness associated to the shoulder region and it has been under diagnosed. Due to high recurrence in different types of tendon injuries, treatments aiming to re-establish tendon functionality have been a focus of research. The aim of this study is to report the implant of a bone marrow mononuclear cell fraction as treatment for bicipital bursitis in a horse. A 7 year old crossbred draught gelding was presented with severe lameness of the left forelimb and pain in the shoulder region. Clinical and ultrasonographic evaluation revealed hemorrhagic synovial fluid, decrease of lameness after shoulder joint anesthesia and bicipital tendon fibers rupture and inflammation. The patient was successfully treated by triamcinolone injection adjacent to the tendon lesion followed by intralesional injection of bone marrow mononuclear cells seven days after the first treatment. Also, rest and controlled exercise were performed. Further clinical and ultrasound evaluations were executed at days 2, 15, 35, 75 and 120. After day 120 the horse started working and despite bicipital bursitis has been reported to exhibit high recurrence, neither clinical nor ultrasonographic signs of recurrence were reported for 15 months after lameness onset. These results suggest that use of regenerative medicine associated to rest and a controlled exercise protocol, accelerated tendon repair, reduced recovery period and allowed successful return to working activities without recurrence.info:eu-repo/semantics/openAccessFacultad de Ciencias Veterinarias, Universidad Austral de ChileArchivos de medicina veterinaria v.44 n.3 20122012-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0301-732X2012000300013en10.4067/S0301-732X2012000300013
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	tendon injuries cell therapy horses shoulder lameness
spellingShingle	tendon injuries cell therapy horses shoulder lameness Menarim,BC Fortini,GA Álvarez,PS Gómez,J Jarrín,CD Ramírez,A Galecio,JS Autologous implant of bone marrow mononuclear stem-cells as treatment for equine bicipital tendonitis: case report
description	Bicipital bursitis in the horse, the inflammation of the bicipital tendon and its surrounding bursa, has been reported to represent a low percentage of lameness cause. However, it is the main cause of lameness associated to the shoulder region and it has been under diagnosed. Due to high recurrence in different types of tendon injuries, treatments aiming to re-establish tendon functionality have been a focus of research. The aim of this study is to report the implant of a bone marrow mononuclear cell fraction as treatment for bicipital bursitis in a horse. A 7 year old crossbred draught gelding was presented with severe lameness of the left forelimb and pain in the shoulder region. Clinical and ultrasonographic evaluation revealed hemorrhagic synovial fluid, decrease of lameness after shoulder joint anesthesia and bicipital tendon fibers rupture and inflammation. The patient was successfully treated by triamcinolone injection adjacent to the tendon lesion followed by intralesional injection of bone marrow mononuclear cells seven days after the first treatment. Also, rest and controlled exercise were performed. Further clinical and ultrasound evaluations were executed at days 2, 15, 35, 75 and 120. After day 120 the horse started working and despite bicipital bursitis has been reported to exhibit high recurrence, neither clinical nor ultrasonographic signs of recurrence were reported for 15 months after lameness onset. These results suggest that use of regenerative medicine associated to rest and a controlled exercise protocol, accelerated tendon repair, reduced recovery period and allowed successful return to working activities without recurrence.
author	Menarim,BC Fortini,GA Álvarez,PS Gómez,J Jarrín,CD Ramírez,A Galecio,JS
author_facet	Menarim,BC Fortini,GA Álvarez,PS Gómez,J Jarrín,CD Ramírez,A Galecio,JS
author_sort	Menarim,BC
title	Autologous implant of bone marrow mononuclear stem-cells as treatment for equine bicipital tendonitis: case report
title_short	Autologous implant of bone marrow mononuclear stem-cells as treatment for equine bicipital tendonitis: case report
title_full	Autologous implant of bone marrow mononuclear stem-cells as treatment for equine bicipital tendonitis: case report
title_fullStr	Autologous implant of bone marrow mononuclear stem-cells as treatment for equine bicipital tendonitis: case report
title_full_unstemmed	Autologous implant of bone marrow mononuclear stem-cells as treatment for equine bicipital tendonitis: case report
title_sort	autologous implant of bone marrow mononuclear stem-cells as treatment for equine bicipital tendonitis: case report
publisher	Facultad de Ciencias Veterinarias, Universidad Austral de Chile
publishDate	2012
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0301-732X2012000300013
work_keys_str_mv	AT menarimbc autologousimplantofbonemarrowmononuclearstemcellsastreatmentforequinebicipitaltendonitiscasereport AT fortiniga autologousimplantofbonemarrowmononuclearstemcellsastreatmentforequinebicipitaltendonitiscasereport AT alvarezps autologousimplantofbonemarrowmononuclearstemcellsastreatmentforequinebicipitaltendonitiscasereport AT gomezj autologousimplantofbonemarrowmononuclearstemcellsastreatmentforequinebicipitaltendonitiscasereport AT jarrincd autologousimplantofbonemarrowmononuclearstemcellsastreatmentforequinebicipitaltendonitiscasereport AT ramireza autologousimplantofbonemarrowmononuclearstemcellsastreatmentforequinebicipitaltendonitiscasereport AT galeciojs autologousimplantofbonemarrowmononuclearstemcellsastreatmentforequinebicipitaltendonitiscasereport
_version_	1718437912292360192

Autologous implant of bone marrow mononuclear stem-cells as treatment for equine bicipital tendonitis: case report

Ejemplares similares