Therapies intended for joint regeneration in the horse

Lameness is the main cause of consultation in the current equine clinic, and osteoarthritis (OA) represents about 60% of cases. During the last decade, there have been significant advances in our understanding of the pathophysiology of OA. However, there has been little progress in the development o...

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Autores principales:	Sandoval,JA, López,C, Carmona,JU
Lenguaje:	English
Publicado:	Facultad de Ciencias Veterinarias, Universidad Austral de Chile 2013
Materias:	horse osteoarthritis regenerative medicine
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0301-732X2013000300002
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spelling	oai:scielo:S0301-732X20130003000022013-12-17Therapies intended for joint regeneration in the horseSandoval,JALópez,CCarmona,JU horse osteoarthritis regenerative medicine Lameness is the main cause of consultation in the current equine clinic, and osteoarthritis (OA) represents about 60% of cases. During the last decade, there have been significant advances in our understanding of the pathophysiology of OA. However, there has been little progress in the development of effective treatments that not only relieve pain and inflammation associated with the problem, but also limit degenerative changes, or even promote regeneration in joint tissues affected by this chronic and inflammatory disease. These treatments should be free of side effects such as gastrointestinal disorders, kidney damage and immunosuppression. Current knowledge about the proteins and cells involved in the biology of musculoskeletal diseases, such as OA, has allowed the development of new therapeutic approaches from an experimental and clinical viewpoint. The aim of this review is to present the state of the art for regenerative therapy of joints in the horse.info:eu-repo/semantics/openAccessFacultad de Ciencias Veterinarias, Universidad Austral de ChileArchivos de medicina veterinaria v.45 n.3 20132013-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0301-732X2013000300002en10.4067/S0301-732X2013000300002
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	horse osteoarthritis regenerative medicine
spellingShingle	horse osteoarthritis regenerative medicine Sandoval,JA López,C Carmona,JU Therapies intended for joint regeneration in the horse
description	Lameness is the main cause of consultation in the current equine clinic, and osteoarthritis (OA) represents about 60% of cases. During the last decade, there have been significant advances in our understanding of the pathophysiology of OA. However, there has been little progress in the development of effective treatments that not only relieve pain and inflammation associated with the problem, but also limit degenerative changes, or even promote regeneration in joint tissues affected by this chronic and inflammatory disease. These treatments should be free of side effects such as gastrointestinal disorders, kidney damage and immunosuppression. Current knowledge about the proteins and cells involved in the biology of musculoskeletal diseases, such as OA, has allowed the development of new therapeutic approaches from an experimental and clinical viewpoint. The aim of this review is to present the state of the art for regenerative therapy of joints in the horse.
author	Sandoval,JA López,C Carmona,JU
author_facet	Sandoval,JA López,C Carmona,JU
author_sort	Sandoval,JA
title	Therapies intended for joint regeneration in the horse
title_short	Therapies intended for joint regeneration in the horse
title_full	Therapies intended for joint regeneration in the horse
title_fullStr	Therapies intended for joint regeneration in the horse
title_full_unstemmed	Therapies intended for joint regeneration in the horse
title_sort	therapies intended for joint regeneration in the horse
publisher	Facultad de Ciencias Veterinarias, Universidad Austral de Chile
publishDate	2013
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0301-732X2013000300002
work_keys_str_mv	AT sandovalja therapiesintendedforjointregenerationinthehorse AT lopezc therapiesintendedforjointregenerationinthehorse AT carmonaju therapiesintendedforjointregenerationinthehorse
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Therapies intended for joint regeneration in the horse

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