Platelet indices in dogs with thrombocytopenia and dogs with normal platelet counts

It is well known that thrombocytopenia is the most commonly acquired haemostatic disorder in dogs and can be potentially life-threatening. With the use of automated analysers, platelet indices such as Mean Platelet Volume (MPV), Platelet Distribution Width (PDW), and Platelet Large Cell Ratio (P-LCR...

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Autores principales:	Souza,AM, Pereira,JJ, Campos,SDE, Torres-Filho,RA, Xavier,MS, Bacellar,DTL, Almosny,NRP
Lenguaje:	English
Publicado:	Facultad de Ciencias Veterinarias, Universidad Austral de Chile 2016
Materias:	platelets anisocytosis blood cell analyzer platelet distribution width
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0301-732X2016000300005
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spelling	oai:scielo:S0301-732X20160003000052016-12-27Platelet indices in dogs with thrombocytopenia and dogs with normal platelet countsSouza,AMPereira,JJCampos,SDETorres-Filho,RAXavier,MSBacellar,DTLAlmosny,NRP platelets anisocytosis blood cell analyzer platelet distribution width It is well known that thrombocytopenia is the most commonly acquired haemostatic disorder in dogs and can be potentially life-threatening. With the use of automated analysers, platelet indices such as Mean Platelet Volume (MPV), Platelet Distribution Width (PDW), and Platelet Large Cell Ratio (P-LCR), became routinely available, allowing data comparison and error checks which results in a more effective quality control. The aim of this study was to evaluate the pattern of platelet indices (MPV, PDW and P-LCR) in dogs with thrombocytopenia and with normal platelet values. The results of 351 CBCs processed in an automated veterinary haematology counter Sysmex® pocH-100iV Diff were analysed. Two groups of dogs were established, those with thrombocytopenia (45) and those with normal platelet counts (306). Thrombocytopenic dogs were subdivided in dogs with less than 150,000 platelets/μL of blood (19/42,2%) and dogs with over 150,000 platelets /μL of blood (26/ 57,8%). Mean values of PDW and P-LCR indices in thrombocytopenic animals were significantly higher than the mean values of animals with normal platelet counts. There was no significant difference in any of the indices in either group of thrombocytopenic dogs. Macroplatelets were present in the blood smears of thrombocytopenic dogs. Results suggested increased thrombopoiesis and release of different sized platelets. It was concluded that both PDW and P-LCR increase in dogs with thrombocytopenia and they are more sensitive than MPV. P-LCR is also important in thrombocytopenic dogs, especially when associated to the presence of large platelets in blood smears.info:eu-repo/semantics/openAccessFacultad de Ciencias Veterinarias, Universidad Austral de ChileArchivos de medicina veterinaria v.48 n.3 20162016-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0301-732X2016000300005en10.4067/S0301-732X2016000300005
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	platelets anisocytosis blood cell analyzer platelet distribution width
spellingShingle	platelets anisocytosis blood cell analyzer platelet distribution width Souza,AM Pereira,JJ Campos,SDE Torres-Filho,RA Xavier,MS Bacellar,DTL Almosny,NRP Platelet indices in dogs with thrombocytopenia and dogs with normal platelet counts
description	It is well known that thrombocytopenia is the most commonly acquired haemostatic disorder in dogs and can be potentially life-threatening. With the use of automated analysers, platelet indices such as Mean Platelet Volume (MPV), Platelet Distribution Width (PDW), and Platelet Large Cell Ratio (P-LCR), became routinely available, allowing data comparison and error checks which results in a more effective quality control. The aim of this study was to evaluate the pattern of platelet indices (MPV, PDW and P-LCR) in dogs with thrombocytopenia and with normal platelet values. The results of 351 CBCs processed in an automated veterinary haematology counter Sysmex® pocH-100iV Diff were analysed. Two groups of dogs were established, those with thrombocytopenia (45) and those with normal platelet counts (306). Thrombocytopenic dogs were subdivided in dogs with less than 150,000 platelets/μL of blood (19/42,2%) and dogs with over 150,000 platelets /μL of blood (26/ 57,8%). Mean values of PDW and P-LCR indices in thrombocytopenic animals were significantly higher than the mean values of animals with normal platelet counts. There was no significant difference in any of the indices in either group of thrombocytopenic dogs. Macroplatelets were present in the blood smears of thrombocytopenic dogs. Results suggested increased thrombopoiesis and release of different sized platelets. It was concluded that both PDW and P-LCR increase in dogs with thrombocytopenia and they are more sensitive than MPV. P-LCR is also important in thrombocytopenic dogs, especially when associated to the presence of large platelets in blood smears.
author	Souza,AM Pereira,JJ Campos,SDE Torres-Filho,RA Xavier,MS Bacellar,DTL Almosny,NRP
author_facet	Souza,AM Pereira,JJ Campos,SDE Torres-Filho,RA Xavier,MS Bacellar,DTL Almosny,NRP
author_sort	Souza,AM
title	Platelet indices in dogs with thrombocytopenia and dogs with normal platelet counts
title_short	Platelet indices in dogs with thrombocytopenia and dogs with normal platelet counts
title_full	Platelet indices in dogs with thrombocytopenia and dogs with normal platelet counts
title_fullStr	Platelet indices in dogs with thrombocytopenia and dogs with normal platelet counts
title_full_unstemmed	Platelet indices in dogs with thrombocytopenia and dogs with normal platelet counts
title_sort	platelet indices in dogs with thrombocytopenia and dogs with normal platelet counts
publisher	Facultad de Ciencias Veterinarias, Universidad Austral de Chile
publishDate	2016
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0301-732X2016000300005
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Platelet indices in dogs with thrombocytopenia and dogs with normal platelet counts

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