Estudio de la respuesta inmune humoral en cerdos infectados con huevos y posoncosferas de Taeina solium

Due to the importance of cysticercosis in Mexico and Latin America and to the fact that in the last years another mechanism of infection for this disease has been proposed, i.e. through postoncospheres and immunosuppression of the host, we have considered relevant to perform the present work, which...

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Autores principales:	Rojas Wastavino,Gloria, Tato Zaldívar,Patricia, SolanoGalvez,Sandra, Herrera Montalvo,Luis, Gutiérrez Quiroz,Manuel, SalazarSchettino,Paz
Lenguaje:	Spanish / Castilian
Publicado:	Programa de Parasitología. Instituto de Ciencias Biomédicas. Facultad de Medicina. Universidad de Chile 1999
Materias:	cisticercosis inmunosupresión cerdos dexametosona
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0365-94021999000300004
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spelling	oai:scielo:S0365-940219990003000042000-10-04Estudio de la respuesta inmune humoral en cerdos infectados con huevos y posoncosferas de Taeina soliumRojas Wastavino,GloriaTato Zaldívar,PatriciaSolanoGalvez,SandraHerrera Montalvo,LuisGutiérrez Quiroz,ManuelSalazarSchettino,Paz cisticercosis inmunosupresión cerdos dexametosona Due to the importance of cysticercosis in Mexico and Latin America and to the fact that in the last years another mechanism of infection for this disease has been proposed, i.e. through postoncospheres and immunosuppression of the host, we have considered relevant to perform the present work, which consisted in assessing the immune response induced by dexamethasone as well as that produced by parasites in pigs infected with T. solium eggs, or postoncosphere-infected, and in postoncosphere-infected and dexamethasone-treated animals. We used 10 recently weaned pigs, three were used as controls, two of them without the drug and one with it; two were infected with T. solium eggs; five with postoncospheres receiving also dexamethasone three of them.We evaluated the humoral response against parasite antigen using indirect haemagglutination (IH) and ELISA methods Results of the immune humoral response revealed titres of up to 1:128 in T. solium eggs infected animals, of 1:16 in postoncosphere infected animals, and of 1:32 towards the end of the experiment in postoncosphere plus dexamethasone animals. Absorbance titres with ELISA confirmed these findings. Data obtained by IH show that the antibody titres of the pigs challenged with postoncospheres and postoncospheres plus dexamethasone are positive as compared to the titres obtained in the pigs infected with T. solium eggs. Results from the ELISA confirmed this finding, since, from weeks 14 to 17, the pigs became positive, behaving as those pigs that developed cysticercosis. This is relevant as it indicates that the antiposcosphere antibodies recognized antigens of T. solium larvae.info:eu-repo/semantics/openAccessPrograma de Parasitología. Instituto de Ciencias Biomédicas. Facultad de Medicina. Universidad de ChileBoletín chileno de parasitología v.54 n.3-4 19991999-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0365-94021999000300004es10.4067/S0365-94021999000300004
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	cisticercosis inmunosupresión cerdos dexametosona
spellingShingle	cisticercosis inmunosupresión cerdos dexametosona Rojas Wastavino,Gloria Tato Zaldívar,Patricia SolanoGalvez,Sandra Herrera Montalvo,Luis Gutiérrez Quiroz,Manuel SalazarSchettino,Paz Estudio de la respuesta inmune humoral en cerdos infectados con huevos y posoncosferas de Taeina solium
description	Due to the importance of cysticercosis in Mexico and Latin America and to the fact that in the last years another mechanism of infection for this disease has been proposed, i.e. through postoncospheres and immunosuppression of the host, we have considered relevant to perform the present work, which consisted in assessing the immune response induced by dexamethasone as well as that produced by parasites in pigs infected with T. solium eggs, or postoncosphere-infected, and in postoncosphere-infected and dexamethasone-treated animals. We used 10 recently weaned pigs, three were used as controls, two of them without the drug and one with it; two were infected with T. solium eggs; five with postoncospheres receiving also dexamethasone three of them.We evaluated the humoral response against parasite antigen using indirect haemagglutination (IH) and ELISA methods Results of the immune humoral response revealed titres of up to 1:128 in T. solium eggs infected animals, of 1:16 in postoncosphere infected animals, and of 1:32 towards the end of the experiment in postoncosphere plus dexamethasone animals. Absorbance titres with ELISA confirmed these findings. Data obtained by IH show that the antibody titres of the pigs challenged with postoncospheres and postoncospheres plus dexamethasone are positive as compared to the titres obtained in the pigs infected with T. solium eggs. Results from the ELISA confirmed this finding, since, from weeks 14 to 17, the pigs became positive, behaving as those pigs that developed cysticercosis. This is relevant as it indicates that the antiposcosphere antibodies recognized antigens of T. solium larvae.
author	Rojas Wastavino,Gloria Tato Zaldívar,Patricia SolanoGalvez,Sandra Herrera Montalvo,Luis Gutiérrez Quiroz,Manuel SalazarSchettino,Paz
author_facet	Rojas Wastavino,Gloria Tato Zaldívar,Patricia SolanoGalvez,Sandra Herrera Montalvo,Luis Gutiérrez Quiroz,Manuel SalazarSchettino,Paz
author_sort	Rojas Wastavino,Gloria
title	Estudio de la respuesta inmune humoral en cerdos infectados con huevos y posoncosferas de Taeina solium
title_short	Estudio de la respuesta inmune humoral en cerdos infectados con huevos y posoncosferas de Taeina solium
title_full	Estudio de la respuesta inmune humoral en cerdos infectados con huevos y posoncosferas de Taeina solium
title_fullStr	Estudio de la respuesta inmune humoral en cerdos infectados con huevos y posoncosferas de Taeina solium
title_full_unstemmed	Estudio de la respuesta inmune humoral en cerdos infectados con huevos y posoncosferas de Taeina solium
title_sort	estudio de la respuesta inmune humoral en cerdos infectados con huevos y posoncosferas de taeina solium
publisher	Programa de Parasitología. Instituto de Ciencias Biomédicas. Facultad de Medicina. Universidad de Chile
publishDate	1999
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0365-94021999000300004
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Estudio de la respuesta inmune humoral en cerdos infectados con huevos y posoncosferas de Taeina solium

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