Utilidad diagnóstica de ELISA IgG, IgM, IgA y Elisa avidez de IgG en toxoplasmosis reciente y crónica

Toxoplasmosis, a world-wide zoonotic infection, is generally asymptomatic and benign in immunocompetent individuals, but it can be serious in immunodeficiencies particulary in patients with acquired immunodeficiency syndrome and in children infected in utero. So, it is important to dispose methods w...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Contreras,María del C., Sandoval,Lea, Salinas,Patricia, Muñoz,Paula, Vargas,Susana
Lenguaje:	Spanish / Castilian
Publicado:	Programa de Parasitología. Instituto de Ciencias Biomédicas. Facultad de Medicina. Universidad de Chile 2000
Materias:	toxoplasmosis inmunodiagnóstico ELISA IgG ELISA IgM ELISA IgA ELISA avidez de IgG
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0365-94022000000100005
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0365-94022000000100005
record_format	dspace
spelling	oai:scielo:S0365-940220000001000052005-07-12Utilidad diagnóstica de ELISA IgG, IgM, IgA y Elisa avidez de IgG en toxoplasmosis reciente y crónicaContreras,María del C.Sandoval,LeaSalinas,PatriciaMuñoz,PaulaVargas,Susana toxoplasmosis inmunodiagnóstico ELISA IgG ELISA IgM ELISA IgA ELISA avidez de IgG Toxoplasmosis, a world-wide zoonotic infection, is generally asymptomatic and benign in immunocompetent individuals, but it can be serious in immunodeficiencies particulary in patients with acquired immunodeficiency syndrome and in children infected in utero. So, it is important to dispose methods which permit discriminate between recent and chronic infections. In order to contribute to improve the diagnosis of toxoplasmosis ELISA IgG, IgM, IgA and ELISA IgG avidity were performed in 15 and 24 sera from patients suspected of having acute and chronic infection respectively, according dye test (DT) titres. ELISA IgG was positive in both groups, ELISA IgM was positive in 78.6 and 58.3% respectively, while ELISA IgA was positive in 85.7 and 33.3% of recent and chronic group respectively. In those sera with low IgG avidity ( 18.8%) we found specific IgM in 71.5 and 4.2% and IgA in 78.6 and 0.0% of recent and chronic groups respectively. Parallely, 208 sera samples were clasified according to the results of DT, indirect hemagglutination and complement fixation tests in the following groups: acute (97), intermediate (36), chronic (35) and negative (40). The results were: acute (96.9-64.9-55.6 and 65.9%); intermediate (97.2-63.8-44.4 and 47.2%); chronic (45.7-42.8- 5.7 and 34.3%) for IgG, IgM, IgA and low IgG avidity respectively. The use of both acute markers, IgA and low IgG avidity in the diagnosis of toxoplasmosis is discussed.info:eu-repo/semantics/openAccessPrograma de Parasitología. Instituto de Ciencias Biomédicas. Facultad de Medicina. Universidad de ChileBoletín chileno de parasitología v.55 n.1-2 20002000-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0365-94022000000100005es10.4067/S0365-94022000000100005
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	toxoplasmosis inmunodiagnóstico ELISA IgG ELISA IgM ELISA IgA ELISA avidez de IgG
spellingShingle	toxoplasmosis inmunodiagnóstico ELISA IgG ELISA IgM ELISA IgA ELISA avidez de IgG Contreras,María del C. Sandoval,Lea Salinas,Patricia Muñoz,Paula Vargas,Susana Utilidad diagnóstica de ELISA IgG, IgM, IgA y Elisa avidez de IgG en toxoplasmosis reciente y crónica
description	Toxoplasmosis, a world-wide zoonotic infection, is generally asymptomatic and benign in immunocompetent individuals, but it can be serious in immunodeficiencies particulary in patients with acquired immunodeficiency syndrome and in children infected in utero. So, it is important to dispose methods which permit discriminate between recent and chronic infections. In order to contribute to improve the diagnosis of toxoplasmosis ELISA IgG, IgM, IgA and ELISA IgG avidity were performed in 15 and 24 sera from patients suspected of having acute and chronic infection respectively, according dye test (DT) titres. ELISA IgG was positive in both groups, ELISA IgM was positive in 78.6 and 58.3% respectively, while ELISA IgA was positive in 85.7 and 33.3% of recent and chronic group respectively. In those sera with low IgG avidity ( 18.8%) we found specific IgM in 71.5 and 4.2% and IgA in 78.6 and 0.0% of recent and chronic groups respectively. Parallely, 208 sera samples were clasified according to the results of DT, indirect hemagglutination and complement fixation tests in the following groups: acute (97), intermediate (36), chronic (35) and negative (40). The results were: acute (96.9-64.9-55.6 and 65.9%); intermediate (97.2-63.8-44.4 and 47.2%); chronic (45.7-42.8- 5.7 and 34.3%) for IgG, IgM, IgA and low IgG avidity respectively. The use of both acute markers, IgA and low IgG avidity in the diagnosis of toxoplasmosis is discussed.
author	Contreras,María del C. Sandoval,Lea Salinas,Patricia Muñoz,Paula Vargas,Susana
author_facet	Contreras,María del C. Sandoval,Lea Salinas,Patricia Muñoz,Paula Vargas,Susana
author_sort	Contreras,María del C.
title	Utilidad diagnóstica de ELISA IgG, IgM, IgA y Elisa avidez de IgG en toxoplasmosis reciente y crónica
title_short	Utilidad diagnóstica de ELISA IgG, IgM, IgA y Elisa avidez de IgG en toxoplasmosis reciente y crónica
title_full	Utilidad diagnóstica de ELISA IgG, IgM, IgA y Elisa avidez de IgG en toxoplasmosis reciente y crónica
title_fullStr	Utilidad diagnóstica de ELISA IgG, IgM, IgA y Elisa avidez de IgG en toxoplasmosis reciente y crónica
title_full_unstemmed	Utilidad diagnóstica de ELISA IgG, IgM, IgA y Elisa avidez de IgG en toxoplasmosis reciente y crónica
title_sort	utilidad diagnóstica de elisa igg, igm, iga y elisa avidez de igg en toxoplasmosis reciente y crónica
publisher	Programa de Parasitología. Instituto de Ciencias Biomédicas. Facultad de Medicina. Universidad de Chile
publishDate	2000
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0365-94022000000100005
work_keys_str_mv	AT contrerasmariadelc utilidaddiagnosticadeelisaiggigmigayelisaavidezdeiggentoxoplasmosisrecienteycronica AT sandovallea utilidaddiagnosticadeelisaiggigmigayelisaavidezdeiggentoxoplasmosisrecienteycronica AT salinaspatricia utilidaddiagnosticadeelisaiggigmigayelisaavidezdeiggentoxoplasmosisrecienteycronica AT munozpaula utilidaddiagnosticadeelisaiggigmigayelisaavidezdeiggentoxoplasmosisrecienteycronica AT vargassusana utilidaddiagnosticadeelisaiggigmigayelisaavidezdeiggentoxoplasmosisrecienteycronica
_version_	1718438080241729536

Utilidad diagnóstica de ELISA IgG, IgM, IgA y Elisa avidez de IgG en toxoplasmosis reciente y crónica

Ejemplares similares