DNA BINDING ALKALOIDS FROM LOBELIA BRIDGESII HOOK ET ARN AND LOBELIA TUPA L
The methanolic extract of the aerial parts of Lobelia bridgesii and L. tupa (Lobeliaceae) showed activity in the DNA binding assay. Bioassay-guided isolation led to the alkaloids norlobelanidine and norlelobanidine as the main bioactive constituents of othe plant. At 0.50 mg/mL, the percentual DNA b...
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| Auteurs principaux: | , , |
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| Langue: | English |
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Sociedad Chilena de Química
1999
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| Accès en ligne: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0366-16441999000300016 |
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| Résumé: | The methanolic extract of the aerial parts of Lobelia bridgesii and L. tupa (Lobeliaceae) showed activity in the DNA binding assay. Bioassay-guided isolation led to the alkaloids norlobelanidine and norlelobanidine as the main bioactive constituents of othe plant. At 0.50 mg/mL, the percentual DNA binding of both compounds were 79% and 71%, respectively |
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