The Syn-Anti Equilibrium of Guanosine Cyclic 3',5'- Monophosphate and 8-Sustituted Derivatives: A Theoretical Study

ABSTRACT The syn-anti conformational equilibrium for a series of nine cyclic nucleotides was studied at semiempirical AM1 level. The AM1 results indicate that for guanosine cyclic 3',5'-monophosphate and their derivatives substituted at 8-position, the syn-conformers are more stable than t...

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Auteur principal: ALDERETE,JOEL B.
Langue:English
Publié: Sociedad Chilena de Química 2000
Sujets:
AM1
Accès en ligne:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0366-16442000000300004
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