NEW SYNTHESIS AND CHARACTERIZATION OF THE SODIUM 3- N-ACETYLAMINO-2,4,6-TRIIODOBENZOATE: ANTIBACTERIAL ACTIVITY EVALUATION
A new synthesis and chemical characterization by mass and infrared spectroscopy of sodium 3-N-acetylamine-2,4,6-triiodobenzoate (sodium acetrizoate), a compound used as contrast agent, has been developed. For its preparation, a new method consisting of three stages has been worked out, using 3-amino...
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| Autores principales: | , , |
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| Lenguaje: | English |
| Publicado: |
Sociedad Chilena de Química
2002
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| Materias: | |
| Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0366-16442002000100009 |
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| Sumario: | A new synthesis and chemical characterization by mass and infrared spectroscopy of sodium 3-N-acetylamine-2,4,6-triiodobenzoate (sodium acetrizoate), a compound used as contrast agent, has been developed. For its preparation, a new method consisting of three stages has been worked out, using 3-aminobenzoic acid as a substrate. Both the intermediate 4 and the product 5 showed antibacterial activity over Pseudomona aeruginosa ATCC and. Shigella flexneri |
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