A PETHIDINE SELECTIVE POLYMERIC MEMBRANE ELECTRODE

A novel plastic poly (vinyl chloride) membrane electrode based on pethidine-reineckate ion-association complex as ion-exchange site for determination of pethidine hydrochloride in injections and tablets was described, in which the plasticizer was dibutyl phthalate. The linear response covered the ra...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Liu,Zhi Hua., Wen,Meng Liang, Yao,Yun, Xiong,Jie
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2002
Materias:	pethidine hydrochloride polymeric membrane electrode potentiometry pharmaceutical analysis
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0366-16442002000200013
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0366-16442002000200013
record_format	dspace
spelling	oai:scielo:S0366-164420020002000132002-10-14A PETHIDINE SELECTIVE POLYMERIC MEMBRANE ELECTRODELiu,Zhi Hua.Wen,Meng LiangYao,YunXiong,Jie pethidine hydrochloride polymeric membrane electrode potentiometry pharmaceutical analysis A novel plastic poly (vinyl chloride) membrane electrode based on pethidine-reineckate ion-association complex as ion-exchange site for determination of pethidine hydrochloride in injections and tablets was described, in which the plasticizer was dibutyl phthalate. The linear response covered the range of 1x10-5~1x10-3 M drug concentration with a slope of 53.50 mV/decade. The practical pH range was 2~8. The lower detection limit was 4.36x10-6 M. There was negligible interference from a number of inorganic and organic cations and some common drug excipients. The proposed electrode had been successfully applied to determine pethidine hydrochloride in tablets and injections. The results were correlated well with those obtained by the United States Pharmacopoeia standard procedureinfo:eu-repo/semantics/openAccessSociedad Chilena de QuímicaBoletín de la Sociedad Chilena de Química v.47 n.2 20022002-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0366-16442002000200013en10.4067/S0366-16442002000200013
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	pethidine hydrochloride polymeric membrane electrode potentiometry pharmaceutical analysis
spellingShingle	pethidine hydrochloride polymeric membrane electrode potentiometry pharmaceutical analysis Liu,Zhi Hua. Wen,Meng Liang Yao,Yun Xiong,Jie A PETHIDINE SELECTIVE POLYMERIC MEMBRANE ELECTRODE
description	A novel plastic poly (vinyl chloride) membrane electrode based on pethidine-reineckate ion-association complex as ion-exchange site for determination of pethidine hydrochloride in injections and tablets was described, in which the plasticizer was dibutyl phthalate. The linear response covered the range of 1x10-5~1x10-3 M drug concentration with a slope of 53.50 mV/decade. The practical pH range was 2~8. The lower detection limit was 4.36x10-6 M. There was negligible interference from a number of inorganic and organic cations and some common drug excipients. The proposed electrode had been successfully applied to determine pethidine hydrochloride in tablets and injections. The results were correlated well with those obtained by the United States Pharmacopoeia standard procedure
author	Liu,Zhi Hua. Wen,Meng Liang Yao,Yun Xiong,Jie
author_facet	Liu,Zhi Hua. Wen,Meng Liang Yao,Yun Xiong,Jie
author_sort	Liu,Zhi Hua.
title	A PETHIDINE SELECTIVE POLYMERIC MEMBRANE ELECTRODE
title_short	A PETHIDINE SELECTIVE POLYMERIC MEMBRANE ELECTRODE
title_full	A PETHIDINE SELECTIVE POLYMERIC MEMBRANE ELECTRODE
title_fullStr	A PETHIDINE SELECTIVE POLYMERIC MEMBRANE ELECTRODE
title_full_unstemmed	A PETHIDINE SELECTIVE POLYMERIC MEMBRANE ELECTRODE
title_sort	pethidine selective polymeric membrane electrode
publisher	Sociedad Chilena de Química
publishDate	2002
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0366-16442002000200013
work_keys_str_mv	AT liuzhihua apethidineselectivepolymericmembraneelectrode AT wenmengliang apethidineselectivepolymericmembraneelectrode AT yaoyun apethidineselectivepolymericmembraneelectrode AT xiongjie apethidineselectivepolymericmembraneelectrode AT liuzhihua pethidineselectivepolymericmembraneelectrode AT wenmengliang pethidineselectivepolymericmembraneelectrode AT yaoyun pethidineselectivepolymericmembraneelectrode AT xiongjie pethidineselectivepolymericmembraneelectrode
_version_	1718438145304821760

A PETHIDINE SELECTIVE POLYMERIC MEMBRANE ELECTRODE

Ejemplares similares