Tetraazamacrocyclic Complexes of Tin(II): Synthesis Spectroscopy and Biological screening

Sixteen to eighteen membered tetraamide macrocyclic ligands N4L¹ and N4L² have been prepared by the condensation of 1,2-diaminoethane or 1,3-diaminopropane with phthalic acid in the presence of condensing reagents dicyclohexylcarbodiimide and 4- dimethylaminopyridine. On reduction, these macrocyclic...

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Autores principales:	CHAUDHARY,ASHU, SWAROOP,RATAN, SINGH,R.
Lenguaje:	English
Publicado:	Sociedad Chilena de Química 2002
Materias:	Teraazamacrocycles complexes synthesis Spectroscopy
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0366-16442002000300002
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spelling	oai:scielo:S0366-164420020003000022014-08-20Tetraazamacrocyclic Complexes of Tin(II): Synthesis Spectroscopy and Biological screeningCHAUDHARY,ASHUSWAROOP,RATANSINGH,R. Teraazamacrocycles complexes synthesis Spectroscopy Sixteen to eighteen membered tetraamide macrocyclic ligands N4L¹ and N4L² have been prepared by the condensation of 1,2-diaminoethane or 1,3-diaminopropane with phthalic acid in the presence of condensing reagents dicyclohexylcarbodiimide and 4- dimethylaminopyridine. On reduction, these macrocyclic ligands give new tetraazamacrocycles N4L³ and N4L4 which form complexes with tin(II) chloride. The macrocyclic ligands and their complexes have been characterized by elemental analysis, molecular weight determinations, conductance, IR and ¹H NMR spectral studies. The spectral data suggested hexacoordinated state for tin in these complexes. Conductivity data suggested that they behave as non-electrolytes. An octahedral geometry for these complexes has been proposed as the binding sites are the nitrogen atoms of the macrocycles. The formulation of the complexes of the type [Sn(N4Ln)Cl2] has been established on the basis of chemical composition. The ligands and their complexes have been screened in vitro against a number of pathogenic fungi and bacteria to assess their growth inhibiting potentialinfo:eu-repo/semantics/openAccessSociedad Chilena de QuímicaBoletín de la Sociedad Chilena de Química v.47 n.3 20022002-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0366-16442002000300002en10.4067/S0366-16442002000300002
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Teraazamacrocycles complexes synthesis Spectroscopy
spellingShingle	Teraazamacrocycles complexes synthesis Spectroscopy CHAUDHARY,ASHU SWAROOP,RATAN SINGH,R. Tetraazamacrocyclic Complexes of Tin(II): Synthesis Spectroscopy and Biological screening
description	Sixteen to eighteen membered tetraamide macrocyclic ligands N4L¹ and N4L² have been prepared by the condensation of 1,2-diaminoethane or 1,3-diaminopropane with phthalic acid in the presence of condensing reagents dicyclohexylcarbodiimide and 4- dimethylaminopyridine. On reduction, these macrocyclic ligands give new tetraazamacrocycles N4L³ and N4L4 which form complexes with tin(II) chloride. The macrocyclic ligands and their complexes have been characterized by elemental analysis, molecular weight determinations, conductance, IR and ¹H NMR spectral studies. The spectral data suggested hexacoordinated state for tin in these complexes. Conductivity data suggested that they behave as non-electrolytes. An octahedral geometry for these complexes has been proposed as the binding sites are the nitrogen atoms of the macrocycles. The formulation of the complexes of the type [Sn(N4Ln)Cl2] has been established on the basis of chemical composition. The ligands and their complexes have been screened in vitro against a number of pathogenic fungi and bacteria to assess their growth inhibiting potential
author	CHAUDHARY,ASHU SWAROOP,RATAN SINGH,R.
author_facet	CHAUDHARY,ASHU SWAROOP,RATAN SINGH,R.
author_sort	CHAUDHARY,ASHU
title	Tetraazamacrocyclic Complexes of Tin(II): Synthesis Spectroscopy and Biological screening
title_short	Tetraazamacrocyclic Complexes of Tin(II): Synthesis Spectroscopy and Biological screening
title_full	Tetraazamacrocyclic Complexes of Tin(II): Synthesis Spectroscopy and Biological screening
title_fullStr	Tetraazamacrocyclic Complexes of Tin(II): Synthesis Spectroscopy and Biological screening
title_full_unstemmed	Tetraazamacrocyclic Complexes of Tin(II): Synthesis Spectroscopy and Biological screening
title_sort	tetraazamacrocyclic complexes of tin(ii): synthesis spectroscopy and biological screening
publisher	Sociedad Chilena de Química
publishDate	2002
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0366-16442002000300002
work_keys_str_mv	AT chaudharyashu tetraazamacrocycliccomplexesoftiniisynthesisspectroscopyandbiologicalscreening AT swaroopratan tetraazamacrocycliccomplexesoftiniisynthesisspectroscopyandbiologicalscreening AT singhr tetraazamacrocycliccomplexesoftiniisynthesisspectroscopyandbiologicalscreening
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Tetraazamacrocyclic Complexes of Tin(II): Synthesis Spectroscopy and Biological screening

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