Resistencia inducible a clindamicina en Staphylococcus aureus meticilino resistente

The increase in methicillin-resistant Staphylococcus aureus (MRSA) infections has limited the use of efective available antibiotics. Clindamycin, an alternative against MRSA, might have inducible resistance that is not detected by common antibiograms. The disk diffusion method (D-test) detects the i...

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Autores principales:	MONTOYA C,IRENE, MIRA O,MAGDALENA, ÁLVAREZ A,ISABEL, COFRE G,JOSÉ, COHEN V,JACOB, DONOSO W,GLORIA, TORRES T,JUAN PABLO
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Chilena de Pediatría 2009
Materias:	Clindamycin antibiotic resistance antibiotics Staphylococcus aureus Clindamicina resistencia antibiótico
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0370-41062009000100006
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spelling	oai:scielo:S0370-410620090001000062009-06-16Resistencia inducible a clindamicina en Staphylococcus aureus meticilino resistenteMONTOYA C,IRENEMIRA O,MAGDALENAÁLVAREZ A,ISABELCOFRE G,JOSÉCOHEN V,JACOBDONOSO W,GLORIATORRES T,JUAN PABLO Clindamycin antibiotic resistance antibiotics Staphylococcus aureus Clindamicina resistencia antibiótico Staphylococcus aureus The increase in methicillin-resistant Staphylococcus aureus (MRSA) infections has limited the use of efective available antibiotics. Clindamycin, an alternative against MRSA, might have inducible resistance that is not detected by common antibiograms. The disk diffusion method (D-test) detects the inducible resistance. Objetive: To establish the frecuency of inducible resistance in MRSA from blood and secretion samples obtained from hospitalyzed patients. Methods: Prospective and descriptive research, including MRSA positive blood and secretion samples from patients of Hospital Luis Calvo Mackenna, between July 2005-July 2006. A D-test was performed to the samples. Results: 220 MRSA samples were obtained and D-test was performed on 155 of them. 80% of the samples carne from tracheobronquial secretion and 90%> had used antibiotics. From all analyzed MRSA isolates, 32 (20.6%o) were Clindamycin susceptible and 14 (43.8%) had Clindamycin inducible resistance (D-test+). Conclusions: A high percentage of MRSA Clindamycin resistant was found. From MRSA Clindamycin susceptible, 43.8%> had Clindamycin inducible resistance (D test+). D-test was implemented in the Microbiology Laboratory at Hospital Luis Calvo Mackenna, allowing the identification of MRSA isolates suceptible to Clindamicyn treatment.info:eu-repo/semantics/openAccessSociedad Chilena de PediatríaRevista chilena de pediatría v.80 n.1 20092009-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0370-41062009000100006es10.4067/S0370-41062009000100006
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Clindamycin antibiotic resistance antibiotics Staphylococcus aureus Clindamicina resistencia antibiótico Staphylococcus aureus
spellingShingle	Clindamycin antibiotic resistance antibiotics Staphylococcus aureus Clindamicina resistencia antibiótico Staphylococcus aureus MONTOYA C,IRENE MIRA O,MAGDALENA ÁLVAREZ A,ISABEL COFRE G,JOSÉ COHEN V,JACOB DONOSO W,GLORIA TORRES T,JUAN PABLO Resistencia inducible a clindamicina en Staphylococcus aureus meticilino resistente
description	The increase in methicillin-resistant Staphylococcus aureus (MRSA) infections has limited the use of efective available antibiotics. Clindamycin, an alternative against MRSA, might have inducible resistance that is not detected by common antibiograms. The disk diffusion method (D-test) detects the inducible resistance. Objetive: To establish the frecuency of inducible resistance in MRSA from blood and secretion samples obtained from hospitalyzed patients. Methods: Prospective and descriptive research, including MRSA positive blood and secretion samples from patients of Hospital Luis Calvo Mackenna, between July 2005-July 2006. A D-test was performed to the samples. Results: 220 MRSA samples were obtained and D-test was performed on 155 of them. 80% of the samples carne from tracheobronquial secretion and 90%> had used antibiotics. From all analyzed MRSA isolates, 32 (20.6%o) were Clindamycin susceptible and 14 (43.8%) had Clindamycin inducible resistance (D-test+). Conclusions: A high percentage of MRSA Clindamycin resistant was found. From MRSA Clindamycin susceptible, 43.8%> had Clindamycin inducible resistance (D test+). D-test was implemented in the Microbiology Laboratory at Hospital Luis Calvo Mackenna, allowing the identification of MRSA isolates suceptible to Clindamicyn treatment.
author	MONTOYA C,IRENE MIRA O,MAGDALENA ÁLVAREZ A,ISABEL COFRE G,JOSÉ COHEN V,JACOB DONOSO W,GLORIA TORRES T,JUAN PABLO
author_facet	MONTOYA C,IRENE MIRA O,MAGDALENA ÁLVAREZ A,ISABEL COFRE G,JOSÉ COHEN V,JACOB DONOSO W,GLORIA TORRES T,JUAN PABLO
author_sort	MONTOYA C,IRENE
title	Resistencia inducible a clindamicina en Staphylococcus aureus meticilino resistente
title_short	Resistencia inducible a clindamicina en Staphylococcus aureus meticilino resistente
title_full	Resistencia inducible a clindamicina en Staphylococcus aureus meticilino resistente
title_fullStr	Resistencia inducible a clindamicina en Staphylococcus aureus meticilino resistente
title_full_unstemmed	Resistencia inducible a clindamicina en Staphylococcus aureus meticilino resistente
title_sort	resistencia inducible a clindamicina en staphylococcus aureus meticilino resistente
publisher	Sociedad Chilena de Pediatría
publishDate	2009
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0370-41062009000100006
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_version_	1718439009918648320

Resistencia inducible a clindamicina en Staphylococcus aureus meticilino resistente

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