Actualización en Presentación y Patogénesis de la Displasia Broncopulmonar

Bronchopulmonary dysplasia (BPD) remains as the most frequent chronic lung disease seen among babies with very low birth weight, contributing to their morbidity and mortality. An increase in the survival of very immature babies due to improvement in pre and post natal care, has resulted in an increa...

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Autor principal:	BANCALARI M,ALDO
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Chilena de Pediatría 2009
Materias:	Bronchopulmonary dysplasia prematurity oxygen therapy mechanical ventilation ductus arteriosus Displasia broncopulmonar prematuridad oxígenoterapia ventilación mecánica ductus arterioso persistente
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0370-41062009000300002
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spelling	oai:scielo:S0370-410620090003000022009-08-27Actualización en Presentación y Patogénesis de la Displasia BroncopulmonarBANCALARI M,ALDO Bronchopulmonary dysplasia prematurity oxygen therapy mechanical ventilation ductus arteriosus Displasia broncopulmonar prematuridad oxígenoterapia ventilación mecánica ductus arterioso persistente Bronchopulmonary dysplasia (BPD) remains as the most frequent chronic lung disease seen among babies with very low birth weight, contributing to their morbidity and mortality. An increase in the survival of very immature babies due to improvement in pre and post natal care, has resulted in an increase in the number of newborns with BDP, although there have been no changes in the actual incidence of the disease. Objective: Lo describe the evolution of DBP in recent decades, the current definition, and to describe and analyze the risk factors involved in the pathogenesis of this disease. Until a few years ago, the terms BPD and chronic lung disease were used as synonyms. After the workshop sponsored by the National Institute of Health in the United States in 2001, it was recommended that the term BPD be used to describe the pulmonary sequelae of immature babies. Classic severe BPD, as described by Northway et al over forty years ago, has evolved into milder forms of chronic pulmonary damage, the so-called "new BPD", characterized by impairment of alveolarización and vascularization of the immature lung in response to multiple injuries. BPD is a multifactorial disease where major risk factors are related to pulmonary immaturity, hyperoxia, baro/volutrauma, as well as inflamation and infection. Genetic susceptibility has recently been shown to be another important risk factor. Conclusion: Bronchopulmonary Dysplasia continues to be the most frequent sequelae affecting low birth weight infants. In the past four decades, the disease has been better defined, and new pathogenetic risk factors have been established.info:eu-repo/semantics/openAccessSociedad Chilena de PediatríaRevista chilena de pediatría v.80 n.3 20092009-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0370-41062009000300002es10.4067/S0370-41062009000300002
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Bronchopulmonary dysplasia prematurity oxygen therapy mechanical ventilation ductus arteriosus Displasia broncopulmonar prematuridad oxígenoterapia ventilación mecánica ductus arterioso persistente
spellingShingle	Bronchopulmonary dysplasia prematurity oxygen therapy mechanical ventilation ductus arteriosus Displasia broncopulmonar prematuridad oxígenoterapia ventilación mecánica ductus arterioso persistente BANCALARI M,ALDO Actualización en Presentación y Patogénesis de la Displasia Broncopulmonar
description	Bronchopulmonary dysplasia (BPD) remains as the most frequent chronic lung disease seen among babies with very low birth weight, contributing to their morbidity and mortality. An increase in the survival of very immature babies due to improvement in pre and post natal care, has resulted in an increase in the number of newborns with BDP, although there have been no changes in the actual incidence of the disease. Objective: Lo describe the evolution of DBP in recent decades, the current definition, and to describe and analyze the risk factors involved in the pathogenesis of this disease. Until a few years ago, the terms BPD and chronic lung disease were used as synonyms. After the workshop sponsored by the National Institute of Health in the United States in 2001, it was recommended that the term BPD be used to describe the pulmonary sequelae of immature babies. Classic severe BPD, as described by Northway et al over forty years ago, has evolved into milder forms of chronic pulmonary damage, the so-called "new BPD", characterized by impairment of alveolarización and vascularization of the immature lung in response to multiple injuries. BPD is a multifactorial disease where major risk factors are related to pulmonary immaturity, hyperoxia, baro/volutrauma, as well as inflamation and infection. Genetic susceptibility has recently been shown to be another important risk factor. Conclusion: Bronchopulmonary Dysplasia continues to be the most frequent sequelae affecting low birth weight infants. In the past four decades, the disease has been better defined, and new pathogenetic risk factors have been established.
author	BANCALARI M,ALDO
author_facet	BANCALARI M,ALDO
author_sort	BANCALARI M,ALDO
title	Actualización en Presentación y Patogénesis de la Displasia Broncopulmonar
title_short	Actualización en Presentación y Patogénesis de la Displasia Broncopulmonar
title_full	Actualización en Presentación y Patogénesis de la Displasia Broncopulmonar
title_fullStr	Actualización en Presentación y Patogénesis de la Displasia Broncopulmonar
title_full_unstemmed	Actualización en Presentación y Patogénesis de la Displasia Broncopulmonar
title_sort	actualización en presentación y patogénesis de la displasia broncopulmonar
publisher	Sociedad Chilena de Pediatría
publishDate	2009
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0370-41062009000300002
work_keys_str_mv	AT bancalarimaldo actualizacionenpresentacionypatogenesisdeladisplasiabroncopulmonar
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Actualización en Presentación y Patogénesis de la Displasia Broncopulmonar

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