Takayasu arteritis in childhood, a clinical case

Background: Takayasu arteritis (TA) is a large vessel systemic vasculitis, affecting the aorta and its main branches, leading to stenosis, thrombosis, and aneurysm formation. Incidence of 2.6 cases per million per year has been reported. TA is rare condition in children. Steroids are the main therap...

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Autores principales: ABARZÚA C,CAROLINA, SOTO M,SARA, GONZÁLEZ G,GLORIA, SAITÚA D,FRANCISCO, DOLZ A,ADOLFO, GUEVARA V,MERCEDES, ACUÑA A,CARLOS
Lenguaje:English
Publicado: Sociedad Chilena de Pediatría 2011
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0370-41062011000100008
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spelling oai:scielo:S0370-410620110001000082014-05-22Takayasu arteritis in childhood, a clinical caseABARZÚA C,CAROLINASOTO M,SARAGONZÁLEZ G,GLORIASAITÚA D,FRANCISCODOLZ A,ADOLFOGUEVARA V,MERCEDESACUÑA A,CARLOS Vasculitis Takayasu Arteritis mesenteric thrombosis steroids immunosuppresor Background: Takayasu arteritis (TA) is a large vessel systemic vasculitis, affecting the aorta and its main branches, leading to stenosis, thrombosis, and aneurysm formation. Incidence of 2.6 cases per million per year has been reported. TA is rare condition in children. Steroids are the main therapy for active disease, however, additional immunosuppressive agents are required in 50% of the patients. Objective: To report a case of TA in a young infant, presenting with intestinal necrosis. Case Report: 12 month-old male diagnosed with TA at 6 month-old, treated with second line immunosupressors. He presented with 3 days of abdominal pain, images showed aneurysm and thrombosis of the superior mesenteric artery. Small bowel ischemia was confirmed. The patient underwent multiple surgical interventions with bowel resection, leaving 30 cm of jejunum and 10 cm of terminal ileum. Anticoagulant therapy was started immediately. Intestinal continuity was restored 6 weeks later, patients was discharge home 3 months after surgery in full enteral intake, anticoagulant therapy, and maintains immunosupressor therapy. Discussion: TA in young infants is uncommon, and they can present atypical clinical manifestations. These patients are a real challenge, requiring multidisciplinary care to avoid further morbidities related to the vasculitis.info:eu-repo/semantics/openAccessSociedad Chilena de PediatríaRevista chilena de pediatría v.82 n.1 20112011-02-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0370-41062011000100008en10.4067/S0370-41062011000100008
institution Scielo Chile
collection Scielo Chile
language English
topic Vasculitis
Takayasu Arteritis
mesenteric thrombosis
steroids
immunosuppresor
spellingShingle Vasculitis
Takayasu Arteritis
mesenteric thrombosis
steroids
immunosuppresor
ABARZÚA C,CAROLINA
SOTO M,SARA
GONZÁLEZ G,GLORIA
SAITÚA D,FRANCISCO
DOLZ A,ADOLFO
GUEVARA V,MERCEDES
ACUÑA A,CARLOS
Takayasu arteritis in childhood, a clinical case
description Background: Takayasu arteritis (TA) is a large vessel systemic vasculitis, affecting the aorta and its main branches, leading to stenosis, thrombosis, and aneurysm formation. Incidence of 2.6 cases per million per year has been reported. TA is rare condition in children. Steroids are the main therapy for active disease, however, additional immunosuppressive agents are required in 50% of the patients. Objective: To report a case of TA in a young infant, presenting with intestinal necrosis. Case Report: 12 month-old male diagnosed with TA at 6 month-old, treated with second line immunosupressors. He presented with 3 days of abdominal pain, images showed aneurysm and thrombosis of the superior mesenteric artery. Small bowel ischemia was confirmed. The patient underwent multiple surgical interventions with bowel resection, leaving 30 cm of jejunum and 10 cm of terminal ileum. Anticoagulant therapy was started immediately. Intestinal continuity was restored 6 weeks later, patients was discharge home 3 months after surgery in full enteral intake, anticoagulant therapy, and maintains immunosupressor therapy. Discussion: TA in young infants is uncommon, and they can present atypical clinical manifestations. These patients are a real challenge, requiring multidisciplinary care to avoid further morbidities related to the vasculitis.
author ABARZÚA C,CAROLINA
SOTO M,SARA
GONZÁLEZ G,GLORIA
SAITÚA D,FRANCISCO
DOLZ A,ADOLFO
GUEVARA V,MERCEDES
ACUÑA A,CARLOS
author_facet ABARZÚA C,CAROLINA
SOTO M,SARA
GONZÁLEZ G,GLORIA
SAITÚA D,FRANCISCO
DOLZ A,ADOLFO
GUEVARA V,MERCEDES
ACUÑA A,CARLOS
author_sort ABARZÚA C,CAROLINA
title Takayasu arteritis in childhood, a clinical case
title_short Takayasu arteritis in childhood, a clinical case
title_full Takayasu arteritis in childhood, a clinical case
title_fullStr Takayasu arteritis in childhood, a clinical case
title_full_unstemmed Takayasu arteritis in childhood, a clinical case
title_sort takayasu arteritis in childhood, a clinical case
publisher Sociedad Chilena de Pediatría
publishDate 2011
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0370-41062011000100008
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