Immune diagnosis of human fasciolosis in children from Cajamarca, Perú

The immunodiagnostic potential of a FAST-ELISA for the detection of antibodies in fasciolosis with sera from 6-12 year old children from Cajamarca, Peru was examined. Four children negative parasitologically were negative by FAST-ELISA. All 13 children found positive parasitologically were also posi...

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Autores principales: HILLYER,GEORGE V., SOLER DE GALANES,MARICELIS, DELGADO AZAÑERO,ELIO
Lenguaje:English
Publicado: Sociedad Chilena de Parasitología.Federación Latinoamericana de Parasitología 2001
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-07202001000300003
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Sumario:The immunodiagnostic potential of a FAST-ELISA for the detection of antibodies in fasciolosis with sera from 6-12 year old children from Cajamarca, Peru was examined. Four children negative parasitologically were negative by FAST-ELISA. All 13 children found positive parasitologically were also positive by FAST-ELISA for 100% sensitivity. Twelve of the 13 infected children seroreverted 4 months post dihydroemetine therapy showing lower antibody levels as compared with the pretreatment sample. These results suggest that FAST-ELISA may be useful for the determination of infection and success of therapy in children with fasciolosis.