Sexagesimal scale for mapping human genome

In a previous work I designed a diagram of the human genome based on a circular ideogram of the haploid set of chromosomes, using a low resolution scale of Megabase units. The purpose of this work is to draft a new scale to measure the physical map of the human genome at the highest resolution level...

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Autor principal:	CRUZ-COKE,RICARDO
Lenguaje:	English
Publicado:	Sociedad de Biología de Chile 2001
Materias:	human genome DNA chromosomes genetic map
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-078X2001000000014
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spelling	oai:scielo:S0716-078X20010000000142001-06-27Sexagesimal scale for mapping human genomeCRUZ-COKE,RICARDO human genome DNA chromosomes genetic map In a previous work I designed a diagram of the human genome based on a circular ideogram of the haploid set of chromosomes, using a low resolution scale of Megabase units. The purpose of this work is to draft a new scale to measure the physical map of the human genome at the highest resolution level. The entire length of the haploid genome of males is deployed in a circumference, marked with a sexagesimal scale with 360 degrees and 1296000 arc seconds. The radio of this circunference displays a semilogaritmic metric scale from 1 m up to the nanometer level. The base pair level of DNA sequences, 10-9 of this circunsference, is measured in milliarsec unit (mas), equivalent to a thousand of arcsecond. The "mas" unit, correspond to 1.27 nanometers (nm) or 0.427 base pair (bp) and it is the framework for measure DNA sequences. Thus the three billion base pairs of the human genome may be identified by 1296000000 "mas" units in continous correlation from number 1 to number 1296000000. This sexagesimal scale covers all the levels of the nuclear genetic material, from nucleotides to chromosomes. The locations of every codon and every gene may be numbered in the physical map of chomosome regions according to this new scale, instead of the partial kilobase and Megabase scales used today. The advantage of the new scale is the unification of the set of chromosomes under a continous scale of measurement at the DNA level, facilitating the correlation with the phenotypes of man and other speciesinfo:eu-repo/semantics/openAccessSociedad de Biología de ChileRevista chilena de historia natural v.74 n.1 20012001-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-078X2001000000014en10.4067/S0716-078X2001000000014
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	human genome DNA chromosomes genetic map
spellingShingle	human genome DNA chromosomes genetic map CRUZ-COKE,RICARDO Sexagesimal scale for mapping human genome
description	In a previous work I designed a diagram of the human genome based on a circular ideogram of the haploid set of chromosomes, using a low resolution scale of Megabase units. The purpose of this work is to draft a new scale to measure the physical map of the human genome at the highest resolution level. The entire length of the haploid genome of males is deployed in a circumference, marked with a sexagesimal scale with 360 degrees and 1296000 arc seconds. The radio of this circunference displays a semilogaritmic metric scale from 1 m up to the nanometer level. The base pair level of DNA sequences, 10-9 of this circunsference, is measured in milliarsec unit (mas), equivalent to a thousand of arcsecond. The "mas" unit, correspond to 1.27 nanometers (nm) or 0.427 base pair (bp) and it is the framework for measure DNA sequences. Thus the three billion base pairs of the human genome may be identified by 1296000000 "mas" units in continous correlation from number 1 to number 1296000000. This sexagesimal scale covers all the levels of the nuclear genetic material, from nucleotides to chromosomes. The locations of every codon and every gene may be numbered in the physical map of chomosome regions according to this new scale, instead of the partial kilobase and Megabase scales used today. The advantage of the new scale is the unification of the set of chromosomes under a continous scale of measurement at the DNA level, facilitating the correlation with the phenotypes of man and other species
author	CRUZ-COKE,RICARDO
author_facet	CRUZ-COKE,RICARDO
author_sort	CRUZ-COKE,RICARDO
title	Sexagesimal scale for mapping human genome
title_short	Sexagesimal scale for mapping human genome
title_full	Sexagesimal scale for mapping human genome
title_fullStr	Sexagesimal scale for mapping human genome
title_full_unstemmed	Sexagesimal scale for mapping human genome
title_sort	sexagesimal scale for mapping human genome
publisher	Sociedad de Biología de Chile
publishDate	2001
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-078X2001000000014
work_keys_str_mv	AT cruzcokericardo sexagesimalscaleformappinghumangenome
_version_	1718439500479201280

Sexagesimal scale for mapping human genome

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