Patrones de sensibilidad in vitro y comportamiento clínico de Shigella

Shigella is an important cause of diarrhea in children, with an increasing prevalence of antibiotic resistance during the past years making the choice of an empiric therapy in dysentery difficult. Between 1997 and 1999, 163 isolated Shigella strains were studied in vitro for susceptibility to antibi...

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Autores principales:	DELPIANO M.,LUIS, TEJERINA M.,HUGO, CONA T.,ERNA, AVILES L.,CARMEN L.
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Chilena de Infectología 2001
Materias:	Shigella Shigellosis Dysentery Diarrhea Treatment
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-10182001000200004
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spelling	oai:scielo:S0716-101820010002000042001-07-24Patrones de sensibilidad in vitro y comportamiento clínico de ShigellaDELPIANO M.,LUISTEJERINA M.,HUGOCONA T.,ERNAAVILES L.,CARMEN L. Shigella Shigellosis Dysentery Diarrhea Treatment Shigella is an important cause of diarrhea in children, with an increasing prevalence of antibiotic resistance during the past years making the choice of an empiric therapy in dysentery difficult. Between 1997 and 1999, 163 isolated Shigella strains were studied in vitro for susceptibility to antibiotics. S. sonnei represented 63% of the isolated strains. Antimicrobial resistance patterns have increased, specially for commonly used antimicrobials. The strains studied were 95% resistant to ampicillin, 84% to chloramphenicol, 43.6% to cotrimoxazole and 3.7% to furazolidone. There was no resistance to ciprofloxacin. Fifty seven children with shigellosis were admited into the hospital, 82.5% of them were older than two years. All the patients were feverish, 56% had dysentery and 8.8% had seizures. Six patient with a torpid evolution and therapeutic failure received ciprofloxacin with eventual clinical success. Ciprofloxacin represents an effective alternative empiric therapy in children with dysenteric diarrhea, which should be evaluated. The need of surveying the local prevalence of antimicrobial resistance to guide therapy in shigellosis is emphasizedinfo:eu-repo/semantics/openAccessSociedad Chilena de InfectologíaRevista chilena de infectología v.18 n.2 20012001-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-10182001000200004es10.4067/S0716-10182001000200004
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Shigella Shigellosis Dysentery Diarrhea Treatment
spellingShingle	Shigella Shigellosis Dysentery Diarrhea Treatment DELPIANO M.,LUIS TEJERINA M.,HUGO CONA T.,ERNA AVILES L.,CARMEN L. Patrones de sensibilidad in vitro y comportamiento clínico de Shigella
description	Shigella is an important cause of diarrhea in children, with an increasing prevalence of antibiotic resistance during the past years making the choice of an empiric therapy in dysentery difficult. Between 1997 and 1999, 163 isolated Shigella strains were studied in vitro for susceptibility to antibiotics. S. sonnei represented 63% of the isolated strains. Antimicrobial resistance patterns have increased, specially for commonly used antimicrobials. The strains studied were 95% resistant to ampicillin, 84% to chloramphenicol, 43.6% to cotrimoxazole and 3.7% to furazolidone. There was no resistance to ciprofloxacin. Fifty seven children with shigellosis were admited into the hospital, 82.5% of them were older than two years. All the patients were feverish, 56% had dysentery and 8.8% had seizures. Six patient with a torpid evolution and therapeutic failure received ciprofloxacin with eventual clinical success. Ciprofloxacin represents an effective alternative empiric therapy in children with dysenteric diarrhea, which should be evaluated. The need of surveying the local prevalence of antimicrobial resistance to guide therapy in shigellosis is emphasized
author	DELPIANO M.,LUIS TEJERINA M.,HUGO CONA T.,ERNA AVILES L.,CARMEN L.
author_facet	DELPIANO M.,LUIS TEJERINA M.,HUGO CONA T.,ERNA AVILES L.,CARMEN L.
author_sort	DELPIANO M.,LUIS
title	Patrones de sensibilidad in vitro y comportamiento clínico de Shigella
title_short	Patrones de sensibilidad in vitro y comportamiento clínico de Shigella
title_full	Patrones de sensibilidad in vitro y comportamiento clínico de Shigella
title_fullStr	Patrones de sensibilidad in vitro y comportamiento clínico de Shigella
title_full_unstemmed	Patrones de sensibilidad in vitro y comportamiento clínico de Shigella
title_sort	patrones de sensibilidad in vitro y comportamiento clínico de shigella
publisher	Sociedad Chilena de Infectología
publishDate	2001
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-10182001000200004
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Patrones de sensibilidad in vitro y comportamiento clínico de Shigella

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