Inmunohistoquímica en un caso de encefalitis por virus de Epstein Barr

EBV can produce a broad range of CNS disorders such as demye-linative diseases, acute encephalitis, cerebellar ataxia, myelitis, or meningitis. The role of EBV itself in acute encephalitis is not completely clear. Presently we described a 4 years old boy with EBV encephalitis that deceased after res...

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Autores principales:	Calore,Edenilson E, Pérez,Nilda M, Martins,José F, Cárdenas,Paola G
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Chilena de Infectología 2012
Materias:	Mononucleosis infecciosa virus de Epstein-Barr encefalitis inmunohistoquímica EBV vasculitis
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-10182012000700021
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spelling	oai:scielo:S0716-101820120007000212013-11-04Inmunohistoquímica en un caso de encefalitis por virus de Epstein BarrCalore,Edenilson EPérez,Nilda MMartins,José FCárdenas,Paola G Mononucleosis infecciosa virus de Epstein-Barr encefalitis inmunohistoquímica EBV vasculitis EBV can produce a broad range of CNS disorders such as demye-linative diseases, acute encephalitis, cerebellar ataxia, myelitis, or meningitis. The role of EBV itself in acute encephalitis is not completely clear. Presently we described a 4 years old boy with EBV encephalitis that deceased after respiratory distress and cardio-respiratory arrest. At autopsy the most important changes in the brain were focal sub cortical peri-vascular mononuclear inflammation of the cerebral vessels. EBV antigens were demonstrated by immunohistochemistry in some cells of the vascular walls and in some glial cells of the brain. As expected this indicates a predominantly cellular response in the brain. The presence of EBV antigens by immunohistochemistry associated to a scarce inflammatory infiltrate supports the hypothesis that EBV itself plays a major role in the pathogenesis of EBV encephalitis.info:eu-repo/semantics/openAccessSociedad Chilena de InfectologíaRevista chilena de infectología v.29 n.6 20122012-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-10182012000700021es10.4067/S0716-10182012000700021
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Mononucleosis infecciosa virus de Epstein-Barr encefalitis inmunohistoquímica EBV vasculitis
spellingShingle	Mononucleosis infecciosa virus de Epstein-Barr encefalitis inmunohistoquímica EBV vasculitis Calore,Edenilson E Pérez,Nilda M Martins,José F Cárdenas,Paola G Inmunohistoquímica en un caso de encefalitis por virus de Epstein Barr
description	EBV can produce a broad range of CNS disorders such as demye-linative diseases, acute encephalitis, cerebellar ataxia, myelitis, or meningitis. The role of EBV itself in acute encephalitis is not completely clear. Presently we described a 4 years old boy with EBV encephalitis that deceased after respiratory distress and cardio-respiratory arrest. At autopsy the most important changes in the brain were focal sub cortical peri-vascular mononuclear inflammation of the cerebral vessels. EBV antigens were demonstrated by immunohistochemistry in some cells of the vascular walls and in some glial cells of the brain. As expected this indicates a predominantly cellular response in the brain. The presence of EBV antigens by immunohistochemistry associated to a scarce inflammatory infiltrate supports the hypothesis that EBV itself plays a major role in the pathogenesis of EBV encephalitis.
author	Calore,Edenilson E Pérez,Nilda M Martins,José F Cárdenas,Paola G
author_facet	Calore,Edenilson E Pérez,Nilda M Martins,José F Cárdenas,Paola G
author_sort	Calore,Edenilson E
title	Inmunohistoquímica en un caso de encefalitis por virus de Epstein Barr
title_short	Inmunohistoquímica en un caso de encefalitis por virus de Epstein Barr
title_full	Inmunohistoquímica en un caso de encefalitis por virus de Epstein Barr
title_fullStr	Inmunohistoquímica en un caso de encefalitis por virus de Epstein Barr
title_full_unstemmed	Inmunohistoquímica en un caso de encefalitis por virus de Epstein Barr
title_sort	inmunohistoquímica en un caso de encefalitis por virus de epstein barr
publisher	Sociedad Chilena de Infectología
publishDate	2012
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-10182012000700021
work_keys_str_mv	AT caloreedenilsone inmunohistoquimicaenuncasodeencefalitisporvirusdeepsteinbarr AT pereznildam inmunohistoquimicaenuncasodeencefalitisporvirusdeepsteinbarr AT martinsjosef inmunohistoquimicaenuncasodeencefalitisporvirusdeepsteinbarr AT cardenaspaolag inmunohistoquimicaenuncasodeencefalitisporvirusdeepsteinbarr
_version_	1718440287288688640

Inmunohistoquímica en un caso de encefalitis por virus de Epstein Barr

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