Distribution of delta sleep-inducing peptide in the newborn and infant human hypothalamus: an immunohistochemical study

The distribution of delta sleep-inducing peptide immunoreactive cell bodies, fibers, and terminal-like structures was investigated in the normal human hypothalamus during the first postnatal year, using immunohistofluorescence and peroxidase anti-peroxidase techniques. Immunolabeled perikarya were r...

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Autores principales:	NAJIMI,MOHAMED, BENNIS,MOHAMED, MOYSES,EMMANUEL, CHIGR,FATIHA
Lenguaje:	English
Publicado:	Sociedad de Biología de Chile 2001
Materias:	DSIP immunohistochemistry development post-mortem human brain
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602001000100013
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spelling	oai:scielo:S0716-976020010001000132001-09-27Distribution of delta sleep-inducing peptide in the newborn and infant human hypothalamus: an immunohistochemical studyNAJIMI,MOHAMEDBENNIS,MOHAMEDMOYSES,EMMANUELCHIGR,FATIHA DSIP immunohistochemistry development post-mortem human brain The distribution of delta sleep-inducing peptide immunoreactive cell bodies, fibers, and terminal-like structures was investigated in the normal human hypothalamus during the first postnatal year, using immunohistofluorescence and peroxidase anti-peroxidase techniques. Immunolabeled perikarya were relatively few and were mostly scattered through the anterior (preoptic) and mediobasal regions (infundibular nucleus) of the hypothalamus. DSIP-immunoreactive fibers and terminal-like fibers were observed throughout the entire rostro-caudal extent of the hypothalamus. They exhibit high densities in the preoptic region, the organum vasculosum of lamina terminalis, infundibular nucleus and median eminence. Moderate to low densities of DSIP-immunoreactive fibers were observed in the other hypothalamic structures, located in the anterior and mediobasal regions of hypothalamus, such as periventricular, paraventricular, suprachiasmatic, ventromedial, dorsomedial and parafornical nuclei. In the present study, the analysis of the immunohistochemical pattern of DSIP-immunoreactive neuronal elements in the human infant hypothalamus during the first postnatal year provided evidence of the presence of several differences. We have found qualitative age-related changes in the density of DSIP immunoreactivity in several hypothalamic structures such as the anterior region and the median eminenceinfo:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.34 n.1 20012001-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602001000100013en10.4067/S0716-97602001000100013
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	DSIP immunohistochemistry development post-mortem human brain
spellingShingle	DSIP immunohistochemistry development post-mortem human brain NAJIMI,MOHAMED BENNIS,MOHAMED MOYSES,EMMANUEL CHIGR,FATIHA Distribution of delta sleep-inducing peptide in the newborn and infant human hypothalamus: an immunohistochemical study
description	The distribution of delta sleep-inducing peptide immunoreactive cell bodies, fibers, and terminal-like structures was investigated in the normal human hypothalamus during the first postnatal year, using immunohistofluorescence and peroxidase anti-peroxidase techniques. Immunolabeled perikarya were relatively few and were mostly scattered through the anterior (preoptic) and mediobasal regions (infundibular nucleus) of the hypothalamus. DSIP-immunoreactive fibers and terminal-like fibers were observed throughout the entire rostro-caudal extent of the hypothalamus. They exhibit high densities in the preoptic region, the organum vasculosum of lamina terminalis, infundibular nucleus and median eminence. Moderate to low densities of DSIP-immunoreactive fibers were observed in the other hypothalamic structures, located in the anterior and mediobasal regions of hypothalamus, such as periventricular, paraventricular, suprachiasmatic, ventromedial, dorsomedial and parafornical nuclei. In the present study, the analysis of the immunohistochemical pattern of DSIP-immunoreactive neuronal elements in the human infant hypothalamus during the first postnatal year provided evidence of the presence of several differences. We have found qualitative age-related changes in the density of DSIP immunoreactivity in several hypothalamic structures such as the anterior region and the median eminence
author	NAJIMI,MOHAMED BENNIS,MOHAMED MOYSES,EMMANUEL CHIGR,FATIHA
author_facet	NAJIMI,MOHAMED BENNIS,MOHAMED MOYSES,EMMANUEL CHIGR,FATIHA
author_sort	NAJIMI,MOHAMED
title	Distribution of delta sleep-inducing peptide in the newborn and infant human hypothalamus: an immunohistochemical study
title_short	Distribution of delta sleep-inducing peptide in the newborn and infant human hypothalamus: an immunohistochemical study
title_full	Distribution of delta sleep-inducing peptide in the newborn and infant human hypothalamus: an immunohistochemical study
title_fullStr	Distribution of delta sleep-inducing peptide in the newborn and infant human hypothalamus: an immunohistochemical study
title_full_unstemmed	Distribution of delta sleep-inducing peptide in the newborn and infant human hypothalamus: an immunohistochemical study
title_sort	distribution of delta sleep-inducing peptide in the newborn and infant human hypothalamus: an immunohistochemical study
publisher	Sociedad de Biología de Chile
publishDate	2001
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602001000100013
work_keys_str_mv	AT najimimohamed distributionofdeltasleepinducingpeptideinthenewbornandinfanthumanhypothalamusanimmunohistochemicalstudy AT bennismohamed distributionofdeltasleepinducingpeptideinthenewbornandinfanthumanhypothalamusanimmunohistochemicalstudy AT moysesemmanuel distributionofdeltasleepinducingpeptideinthenewbornandinfanthumanhypothalamusanimmunohistochemicalstudy AT chigrfatiha distributionofdeltasleepinducingpeptideinthenewbornandinfanthumanhypothalamusanimmunohistochemicalstudy
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Distribution of delta sleep-inducing peptide in the newborn and infant human hypothalamus: an immunohistochemical study

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