Jaime Alvarez and the case against slow axoplasmic transport: some epistemological reflections

The 'slow axoplasmic transport theory' has been the prevailing view over the last forty years in order to explain the metabolic maintenance of neuronal axons and nerve endings. A significant amount of evidence against this theoretic interpretation of the existing experimental data has been...

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Autor principal:	SERANI-MERLO,ALEJANDRO
Lenguaje:	English
Publicado:	Sociedad de Biología de Chile 2001
Materias:	axon biology biological epistemology neuron slow axonal transport
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602001000200015
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spelling	oai:scielo:S0716-976020010002000152002-01-02Jaime Alvarez and the case against slow axoplasmic transport: some epistemological reflectionsSERANI-MERLO,ALEJANDRO axon biology biological epistemology neuron slow axonal transport The 'slow axoplasmic transport theory' has been the prevailing view over the last forty years in order to explain the metabolic maintenance of neuronal axons and nerve endings. A significant amount of evidence against this theoretic interpretation of the existing experimental data has been presented by J. Alvarez, A. Giuditta and E. Koenig in an exhaustive review. They propose an alternative theoretical interpretation called the 'local synthesis model', integrating recent evidence for axon biology and regeneration. We present some epistemological considerations that reinforce the above criticisms and propositions.info:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.34 n.2 20012001-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602001000200015en10.4067/S0716-97602001000200015
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	axon biology biological epistemology neuron slow axonal transport
spellingShingle	axon biology biological epistemology neuron slow axonal transport SERANI-MERLO,ALEJANDRO Jaime Alvarez and the case against slow axoplasmic transport: some epistemological reflections
description	The 'slow axoplasmic transport theory' has been the prevailing view over the last forty years in order to explain the metabolic maintenance of neuronal axons and nerve endings. A significant amount of evidence against this theoretic interpretation of the existing experimental data has been presented by J. Alvarez, A. Giuditta and E. Koenig in an exhaustive review. They propose an alternative theoretical interpretation called the 'local synthesis model', integrating recent evidence for axon biology and regeneration. We present some epistemological considerations that reinforce the above criticisms and propositions.
author	SERANI-MERLO,ALEJANDRO
author_facet	SERANI-MERLO,ALEJANDRO
author_sort	SERANI-MERLO,ALEJANDRO
title	Jaime Alvarez and the case against slow axoplasmic transport: some epistemological reflections
title_short	Jaime Alvarez and the case against slow axoplasmic transport: some epistemological reflections
title_full	Jaime Alvarez and the case against slow axoplasmic transport: some epistemological reflections
title_fullStr	Jaime Alvarez and the case against slow axoplasmic transport: some epistemological reflections
title_full_unstemmed	Jaime Alvarez and the case against slow axoplasmic transport: some epistemological reflections
title_sort	jaime alvarez and the case against slow axoplasmic transport: some epistemological reflections
publisher	Sociedad de Biología de Chile
publishDate	2001
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602001000200015
work_keys_str_mv	AT seranimerloalejandro jaimealvarezandthecaseagainstslowaxoplasmictransportsomeepistemologicalreflections
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Jaime Alvarez and the case against slow axoplasmic transport: some epistemological reflections

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