Lipid rafts: cell surface platforms for T cell signaling

The Src family tyrosine kinase Lck is essential for T cell development and T cell receptor (TCR)* signaling. Lck is post-translationally fatty acylated at its N-terminus conferring membrane targeting and concentration in plasma membrane lipid rafts, which are lipid-based organisational platforms. Co...

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Autores principales: MAGEE,TONY, PIRINEN,NIINA, ADLER,JEREMY, PAGAKIS,STAMATIS N, PARMRYD,INGELA
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2002
Materias:
Lck
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000200003
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