Molecular interplay between ion channels and the regulation of apoptosis

Apoptosis is the programmed and deliberate destruction of specific cells. This process occurs during normal development and maintains cellular homeostasis. Disruption or malfunction of apoptosis is implicated in diseases like cancer, AIDS as well as neurodegenerative disorders. The movement of monov...

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Autores principales: RAZIK,MONA A, CIDLOWSKI,JOHN A
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2002
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000200011
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spelling oai:scielo:S0716-976020020002000112002-12-26Molecular interplay between ion channels and the regulation of apoptosisRAZIK,MONA ACIDLOWSKI,JOHN AApoptosis is the programmed and deliberate destruction of specific cells. This process occurs during normal development and maintains cellular homeostasis. Disruption or malfunction of apoptosis is implicated in diseases like cancer, AIDS as well as neurodegenerative disorders. The movement of monovalent ions appears to set the stage for the induction of the self-destruction machinery by creating an intracellular environment that favors activation and coordinated execution of the apoptotic program. Understanding the components and steps involved in this intricate process can further our insight to diseases and reveal new approaches for therapeutic treatmentinfo:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.35 n.2 20022002-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000200011en10.4067/S0716-97602002000200011
institution Scielo Chile
collection Scielo Chile
language English
description Apoptosis is the programmed and deliberate destruction of specific cells. This process occurs during normal development and maintains cellular homeostasis. Disruption or malfunction of apoptosis is implicated in diseases like cancer, AIDS as well as neurodegenerative disorders. The movement of monovalent ions appears to set the stage for the induction of the self-destruction machinery by creating an intracellular environment that favors activation and coordinated execution of the apoptotic program. Understanding the components and steps involved in this intricate process can further our insight to diseases and reveal new approaches for therapeutic treatment
author RAZIK,MONA A
CIDLOWSKI,JOHN A
spellingShingle RAZIK,MONA A
CIDLOWSKI,JOHN A
Molecular interplay between ion channels and the regulation of apoptosis
author_facet RAZIK,MONA A
CIDLOWSKI,JOHN A
author_sort RAZIK,MONA A
title Molecular interplay between ion channels and the regulation of apoptosis
title_short Molecular interplay between ion channels and the regulation of apoptosis
title_full Molecular interplay between ion channels and the regulation of apoptosis
title_fullStr Molecular interplay between ion channels and the regulation of apoptosis
title_full_unstemmed Molecular interplay between ion channels and the regulation of apoptosis
title_sort molecular interplay between ion channels and the regulation of apoptosis
publisher Sociedad de Biología de Chile
publishDate 2002
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000200011
work_keys_str_mv AT razikmonaa molecularinterplaybetweenionchannelsandtheregulationofapoptosis
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