Wnt signaling: A complex issue

The development of tissues and organs in multicellular organisms is controlled by the interplay of several signaling pathways that cross-talk to provide positional information and induce cell fate specification. Together with other families of secreted factors such as TGFßs, FGFs, Hedgehog and Notch...

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Autores principales: HENDRIKS,BART, REICHMANN,ERNST
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2002
Materias:
APC
TCF
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000200019
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spelling oai:scielo:S0716-976020020002000192002-12-26Wnt signaling: A complex issueHENDRIKS,BARTREICHMANN,ERNST Wnts frizzled LRP 5/6 ß-catenin APC TCF The development of tissues and organs in multicellular organisms is controlled by the interplay of several signaling pathways that cross-talk to provide positional information and induce cell fate specification. Together with other families of secreted factors such as TGFßs, FGFs, Hedgehog and Notch proteins, Wnt growth factors are crucially implicated in these processes. Here, we will first discuss molecular mechanisms and then consider some biological consequences of Wnt signalinginfo:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.35 n.2 20022002-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000200019en10.4067/S0716-97602002000200019
institution Scielo Chile
collection Scielo Chile
language English
topic Wnts
frizzled
LRP 5/6
ß-catenin
APC
TCF
spellingShingle Wnts
frizzled
LRP 5/6
ß-catenin
APC
TCF
HENDRIKS,BART
REICHMANN,ERNST
Wnt signaling: A complex issue
description The development of tissues and organs in multicellular organisms is controlled by the interplay of several signaling pathways that cross-talk to provide positional information and induce cell fate specification. Together with other families of secreted factors such as TGFßs, FGFs, Hedgehog and Notch proteins, Wnt growth factors are crucially implicated in these processes. Here, we will first discuss molecular mechanisms and then consider some biological consequences of Wnt signaling
author HENDRIKS,BART
REICHMANN,ERNST
author_facet HENDRIKS,BART
REICHMANN,ERNST
author_sort HENDRIKS,BART
title Wnt signaling: A complex issue
title_short Wnt signaling: A complex issue
title_full Wnt signaling: A complex issue
title_fullStr Wnt signaling: A complex issue
title_full_unstemmed Wnt signaling: A complex issue
title_sort wnt signaling: a complex issue
publisher Sociedad de Biología de Chile
publishDate 2002
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000200019
work_keys_str_mv AT hendriksbart wntsignalingacomplexissue
AT reichmannernst wntsignalingacomplexissue
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