uvsZ1 mutation shows epistatic relations with uvsD153 and uvsJ1 mutations without any involvement with checkpoint control in Aspergillus nidulans
The participation of the recently described uvsZ1 mutation in checkpoint control and the identification of epistatic relations between uvsZ1 mutation and uvsD153 and uvsJ1 mutations are provided. The effect of mutation uvsZ1 in mitotic exchanges into paba-bi (chromosome I) and cho-nic (chromosome VI...
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Sociedad de Biología de Chile
2002
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oai:scielo:S0716-976020020003000182003-11-26uvsZ1 mutation shows epistatic relations with uvsD153 and uvsJ1 mutations without any involvement with checkpoint control in Aspergillus nidulansBAPTISTA,FRANCIELLEAVEZUM ALVES DE CASTRO-PRADO,MARIALBA checkpoint pathways DNA repair uvs mutations The participation of the recently described uvsZ1 mutation in checkpoint control and the identification of epistatic relations between uvsZ1 mutation and uvsD153 and uvsJ1 mutations are provided. The effect of mutation uvsZ1 in mitotic exchanges into paba-bi (chromosome I) and cho-nic (chromosome VII) genetic intervals has also been evaluated. The mutation uvsZ1 was epistatic with regard to uvsD153 and uvsJ1 mutations, with no involvement with checkpoint control. In contrast to mutations in UvsB and UvsF groups, the uvsZ1 mutation failed to cause any changes in the frequencies of mitotic crossing-over. The distinct phenotypic traits given by mutation uvsZ1 suggest the presence of complex interactions among the different DNA repair pathways. Interaction may be an additional cell strategy of DNA damage responseinfo:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.35 n.3-4 20022002-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000300018en10.4067/S0716-97602002000300018 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
English |
topic |
checkpoint pathways DNA repair uvs mutations |
spellingShingle |
checkpoint pathways DNA repair uvs mutations BAPTISTA,FRANCIELLE AVEZUM ALVES DE CASTRO-PRADO,MARIALBA uvsZ1 mutation shows epistatic relations with uvsD153 and uvsJ1 mutations without any involvement with checkpoint control in Aspergillus nidulans |
description |
The participation of the recently described uvsZ1 mutation in checkpoint control and the identification of epistatic relations between uvsZ1 mutation and uvsD153 and uvsJ1 mutations are provided. The effect of mutation uvsZ1 in mitotic exchanges into paba-bi (chromosome I) and cho-nic (chromosome VII) genetic intervals has also been evaluated. The mutation uvsZ1 was epistatic with regard to uvsD153 and uvsJ1 mutations, with no involvement with checkpoint control. In contrast to mutations in UvsB and UvsF groups, the uvsZ1 mutation failed to cause any changes in the frequencies of mitotic crossing-over. The distinct phenotypic traits given by mutation uvsZ1 suggest the presence of complex interactions among the different DNA repair pathways. Interaction may be an additional cell strategy of DNA damage response |
author |
BAPTISTA,FRANCIELLE AVEZUM ALVES DE CASTRO-PRADO,MARIALBA |
author_facet |
BAPTISTA,FRANCIELLE AVEZUM ALVES DE CASTRO-PRADO,MARIALBA |
author_sort |
BAPTISTA,FRANCIELLE |
title |
uvsZ1 mutation shows epistatic relations with uvsD153 and uvsJ1 mutations without any involvement with checkpoint control in Aspergillus nidulans |
title_short |
uvsZ1 mutation shows epistatic relations with uvsD153 and uvsJ1 mutations without any involvement with checkpoint control in Aspergillus nidulans |
title_full |
uvsZ1 mutation shows epistatic relations with uvsD153 and uvsJ1 mutations without any involvement with checkpoint control in Aspergillus nidulans |
title_fullStr |
uvsZ1 mutation shows epistatic relations with uvsD153 and uvsJ1 mutations without any involvement with checkpoint control in Aspergillus nidulans |
title_full_unstemmed |
uvsZ1 mutation shows epistatic relations with uvsD153 and uvsJ1 mutations without any involvement with checkpoint control in Aspergillus nidulans |
title_sort |
uvsz1 mutation shows epistatic relations with uvsd153 and uvsj1 mutations without any involvement with checkpoint control in aspergillus nidulans |
publisher |
Sociedad de Biología de Chile |
publishDate |
2002 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000300018 |
work_keys_str_mv |
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