uvsZ1 mutation shows epistatic relations with uvsD153 and uvsJ1 mutations without any involvement with checkpoint control in Aspergillus nidulans

The participation of the recently described uvsZ1 mutation in checkpoint control and the identification of epistatic relations between uvsZ1 mutation and uvsD153 and uvsJ1 mutations are provided. The effect of mutation uvsZ1 in mitotic exchanges into paba-bi (chromosome I) and cho-nic (chromosome VI...

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Autores principales: BAPTISTA,FRANCIELLE, AVEZUM ALVES DE CASTRO-PRADO,MARIALBA
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2002
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000300018
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spelling oai:scielo:S0716-976020020003000182003-11-26uvsZ1 mutation shows epistatic relations with uvsD153 and uvsJ1 mutations without any involvement with checkpoint control in Aspergillus nidulansBAPTISTA,FRANCIELLEAVEZUM ALVES DE CASTRO-PRADO,MARIALBA checkpoint pathways DNA repair uvs mutations The participation of the recently described uvsZ1 mutation in checkpoint control and the identification of epistatic relations between uvsZ1 mutation and uvsD153 and uvsJ1 mutations are provided. The effect of mutation uvsZ1 in mitotic exchanges into paba-bi (chromosome I) and cho-nic (chromosome VII) genetic intervals has also been evaluated. The mutation uvsZ1 was epistatic with regard to uvsD153 and uvsJ1 mutations, with no involvement with checkpoint control. In contrast to mutations in UvsB and UvsF groups, the uvsZ1 mutation failed to cause any changes in the frequencies of mitotic crossing-over. The distinct phenotypic traits given by mutation uvsZ1 suggest the presence of complex interactions among the different DNA repair pathways. Interaction may be an additional cell strategy of DNA damage responseinfo:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.35 n.3-4 20022002-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000300018en10.4067/S0716-97602002000300018
institution Scielo Chile
collection Scielo Chile
language English
topic checkpoint pathways
DNA repair
uvs mutations
spellingShingle checkpoint pathways
DNA repair
uvs mutations
BAPTISTA,FRANCIELLE
AVEZUM ALVES DE CASTRO-PRADO,MARIALBA
uvsZ1 mutation shows epistatic relations with uvsD153 and uvsJ1 mutations without any involvement with checkpoint control in Aspergillus nidulans
description The participation of the recently described uvsZ1 mutation in checkpoint control and the identification of epistatic relations between uvsZ1 mutation and uvsD153 and uvsJ1 mutations are provided. The effect of mutation uvsZ1 in mitotic exchanges into paba-bi (chromosome I) and cho-nic (chromosome VII) genetic intervals has also been evaluated. The mutation uvsZ1 was epistatic with regard to uvsD153 and uvsJ1 mutations, with no involvement with checkpoint control. In contrast to mutations in UvsB and UvsF groups, the uvsZ1 mutation failed to cause any changes in the frequencies of mitotic crossing-over. The distinct phenotypic traits given by mutation uvsZ1 suggest the presence of complex interactions among the different DNA repair pathways. Interaction may be an additional cell strategy of DNA damage response
author BAPTISTA,FRANCIELLE
AVEZUM ALVES DE CASTRO-PRADO,MARIALBA
author_facet BAPTISTA,FRANCIELLE
AVEZUM ALVES DE CASTRO-PRADO,MARIALBA
author_sort BAPTISTA,FRANCIELLE
title uvsZ1 mutation shows epistatic relations with uvsD153 and uvsJ1 mutations without any involvement with checkpoint control in Aspergillus nidulans
title_short uvsZ1 mutation shows epistatic relations with uvsD153 and uvsJ1 mutations without any involvement with checkpoint control in Aspergillus nidulans
title_full uvsZ1 mutation shows epistatic relations with uvsD153 and uvsJ1 mutations without any involvement with checkpoint control in Aspergillus nidulans
title_fullStr uvsZ1 mutation shows epistatic relations with uvsD153 and uvsJ1 mutations without any involvement with checkpoint control in Aspergillus nidulans
title_full_unstemmed uvsZ1 mutation shows epistatic relations with uvsD153 and uvsJ1 mutations without any involvement with checkpoint control in Aspergillus nidulans
title_sort uvsz1 mutation shows epistatic relations with uvsd153 and uvsj1 mutations without any involvement with checkpoint control in aspergillus nidulans
publisher Sociedad de Biología de Chile
publishDate 2002
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602002000300018
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