Regulation of cardiac excitation-contraction coupling by sorcin, a novel modulator of ryanodine receptors

Activation of Ca2+ release channels/ryanodine receptors (RyR) by the inward Ca2+ current (I Ca) gives rise to Ca2+-induced Ca2+ release (CICR), the amplifying Ca2+ signaling mechanism that triggers contraction of the heart. CICR, in theory, is a high-gain, self-regenerating process, but an unidentif...

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Autores principales: FARRELL,EMILY F, ANTARAMIAN,ANAID, BENKUSKY,NANCY, ZHU,XINSHENG, RUEDA,ANGÉLICA, GÓMEZ,ANA M, VALDIVIA,HÉCTOR H
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2004
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000400015
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