1a,25(OH)2D3 induces capacitative calcium entry involving a trpc3 protein in skeletal muscle and osteoblastic cells

This work describes the involvement of TRPC proteins in capacitative calcium entry (CCE) induced by 1a,25-dihydroxy-vitamin-D3 [1a,25(OH)2D3] in chick skeletal muscle and in rat osteoblast-like cells (ROS 17/2.8) and the role of the vitamin D receptor (VDR) in this non-genomic rapid response mediate...

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Autores principales: SANTILLÁN,G, KATZ,S, BUITRAGO,C, BOLAND,R
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2004
Materias:
CCE
VDR
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000400021
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spelling oai:scielo:S0716-976020040004000212005-06-021a,25(OH)2D3 induces capacitative calcium entry involving a trpc3 protein in skeletal muscle and osteoblastic cellsSANTILLÁN,GKATZ,SBUITRAGO,CBOLAND,R CCE TRPC muscle cells osteoblasts 1a,25(OH)2D3 VDR INAD This work describes the involvement of TRPC proteins in capacitative calcium entry (CCE) induced by 1a,25-dihydroxy-vitamin-D3 [1a,25(OH)2D3] in chick skeletal muscle and in rat osteoblast-like cells (ROS 17/2.8) and the role of the vitamin D receptor (VDR) in this non-genomic rapid response mediated by the hormone. We propose that an endogenous TRPC3 protein mediates 1a,25(OH)2D3 modulation of CCE in these cells, which seems to implicate VDR-TRPC3 association and the participation of an INAD-like scaffold protein.info:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.37 n.4 20042004-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000400021en10.4067/S0716-97602004000400021
institution Scielo Chile
collection Scielo Chile
language English
topic CCE
TRPC
muscle cells
osteoblasts
1a,25(OH)2D3
VDR
INAD
spellingShingle CCE
TRPC
muscle cells
osteoblasts
1a,25(OH)2D3
VDR
INAD
SANTILLÁN,G
KATZ,S
BUITRAGO,C
BOLAND,R
1a,25(OH)2D3 induces capacitative calcium entry involving a trpc3 protein in skeletal muscle and osteoblastic cells
description This work describes the involvement of TRPC proteins in capacitative calcium entry (CCE) induced by 1a,25-dihydroxy-vitamin-D3 [1a,25(OH)2D3] in chick skeletal muscle and in rat osteoblast-like cells (ROS 17/2.8) and the role of the vitamin D receptor (VDR) in this non-genomic rapid response mediated by the hormone. We propose that an endogenous TRPC3 protein mediates 1a,25(OH)2D3 modulation of CCE in these cells, which seems to implicate VDR-TRPC3 association and the participation of an INAD-like scaffold protein.
author SANTILLÁN,G
KATZ,S
BUITRAGO,C
BOLAND,R
author_facet SANTILLÁN,G
KATZ,S
BUITRAGO,C
BOLAND,R
author_sort SANTILLÁN,G
title 1a,25(OH)2D3 induces capacitative calcium entry involving a trpc3 protein in skeletal muscle and osteoblastic cells
title_short 1a,25(OH)2D3 induces capacitative calcium entry involving a trpc3 protein in skeletal muscle and osteoblastic cells
title_full 1a,25(OH)2D3 induces capacitative calcium entry involving a trpc3 protein in skeletal muscle and osteoblastic cells
title_fullStr 1a,25(OH)2D3 induces capacitative calcium entry involving a trpc3 protein in skeletal muscle and osteoblastic cells
title_full_unstemmed 1a,25(OH)2D3 induces capacitative calcium entry involving a trpc3 protein in skeletal muscle and osteoblastic cells
title_sort 1a,25(oh)2d3 induces capacitative calcium entry involving a trpc3 protein in skeletal muscle and osteoblastic cells
publisher Sociedad de Biología de Chile
publishDate 2004
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000400021
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AT katzs 1a25oh2d3inducescapacitativecalciumentryinvolvingatrpc3proteininskeletalmuscleandosteoblasticcells
AT buitragoc 1a25oh2d3inducescapacitativecalciumentryinvolvingatrpc3proteininskeletalmuscleandosteoblasticcells
AT bolandr 1a25oh2d3inducescapacitativecalciumentryinvolvingatrpc3proteininskeletalmuscleandosteoblasticcells
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