Isolation, sequencing and phylogenetic analysis of the hemagglutinin, neuraminidase and nucleoprotein genes of the Chilean equine influenza virus subtypes H7N7 and H3N8

We report here on the isolation and sequencing of the hemagglutinin, neuraminidase and nucleoprotein genes of the Chilean equine influenza virus subtypes H7N7 (A⁄equi-1⁄Santiago⁄77, Sa77) and H3N8 (A⁄equi-2⁄Santiago⁄85, Sa85) . The sequence...

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Autores principales:	Müller,Ilse, Jaureguiberry,Beltrán, Valenzuela,Pablo D.T
Lenguaje:	English
Publicado:	Sociedad de Biología de Chile 2005
Materias:	equine influenza hemagglutinin neuraminidase nucleoprotein genes
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602005000100008
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spelling	oai:scielo:S0716-976020050001000082005-07-06Isolation, sequencing and phylogenetic analysis of the hemagglutinin, neuraminidase and nucleoprotein genes of the Chilean equine influenza virus subtypes H7N7 and H3N8Müller,IlseJaureguiberry,BeltránValenzuela,Pablo D.T equine influenza hemagglutinin neuraminidase nucleoprotein genes We report here on the isolation and sequencing of the hemagglutinin, neuraminidase and nucleoprotein genes of the Chilean equine influenza virus subtypes H7N7 (A⁄equi-1⁄Santiago⁄77, Sa77) and H3N8 (A⁄equi-2⁄Santiago⁄85, Sa85) . The sequences obtained allowed a variability analysis, which indicated significant differences when compared with other isolates. We found that Chilean isolates are more similar to the North American variety than to European isolates. Isolate Sa77 is a good candidate for inclusion in a vaccine as it is the latest isolate of the subtype H7N7 and is probably better-adapted to the equine host. Isolate Sa85, of subtype H3N8, also appears to be a good candidate since it has no significant differences in the main antigenic sites with recent isolates.info:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.38 n.1 20052005-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602005000100008en10.4067/S0716-97602005000100008
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	equine influenza hemagglutinin neuraminidase nucleoprotein genes
spellingShingle	equine influenza hemagglutinin neuraminidase nucleoprotein genes Müller,Ilse Jaureguiberry,Beltrán Valenzuela,Pablo D.T Isolation, sequencing and phylogenetic analysis of the hemagglutinin, neuraminidase and nucleoprotein genes of the Chilean equine influenza virus subtypes H7N7 and H3N8
description	We report here on the isolation and sequencing of the hemagglutinin, neuraminidase and nucleoprotein genes of the Chilean equine influenza virus subtypes H7N7 (A⁄equi-1⁄Santiago⁄77, Sa77) and H3N8 (A⁄equi-2⁄Santiago⁄85, Sa85) . The sequences obtained allowed a variability analysis, which indicated significant differences when compared with other isolates. We found that Chilean isolates are more similar to the North American variety than to European isolates. Isolate Sa77 is a good candidate for inclusion in a vaccine as it is the latest isolate of the subtype H7N7 and is probably better-adapted to the equine host. Isolate Sa85, of subtype H3N8, also appears to be a good candidate since it has no significant differences in the main antigenic sites with recent isolates.
author	Müller,Ilse Jaureguiberry,Beltrán Valenzuela,Pablo D.T
author_facet	Müller,Ilse Jaureguiberry,Beltrán Valenzuela,Pablo D.T
author_sort	Müller,Ilse
title	Isolation, sequencing and phylogenetic analysis of the hemagglutinin, neuraminidase and nucleoprotein genes of the Chilean equine influenza virus subtypes H7N7 and H3N8
title_short	Isolation, sequencing and phylogenetic analysis of the hemagglutinin, neuraminidase and nucleoprotein genes of the Chilean equine influenza virus subtypes H7N7 and H3N8
title_full	Isolation, sequencing and phylogenetic analysis of the hemagglutinin, neuraminidase and nucleoprotein genes of the Chilean equine influenza virus subtypes H7N7 and H3N8
title_fullStr	Isolation, sequencing and phylogenetic analysis of the hemagglutinin, neuraminidase and nucleoprotein genes of the Chilean equine influenza virus subtypes H7N7 and H3N8
title_full_unstemmed	Isolation, sequencing and phylogenetic analysis of the hemagglutinin, neuraminidase and nucleoprotein genes of the Chilean equine influenza virus subtypes H7N7 and H3N8
title_sort	isolation, sequencing and phylogenetic analysis of the hemagglutinin, neuraminidase and nucleoprotein genes of the chilean equine influenza virus subtypes h7n7 and h3n8
publisher	Sociedad de Biología de Chile
publishDate	2005
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602005000100008
work_keys_str_mv	AT mullerilse isolationsequencingandphylogeneticanalysisofthehemagglutininneuraminidaseandnucleoproteingenesofthechileanequineinfluenzavirussubtypesh7n7andh3n8 AT jaureguiberrybeltran isolationsequencingandphylogeneticanalysisofthehemagglutininneuraminidaseandnucleoproteingenesofthechileanequineinfluenzavirussubtypesh7n7andh3n8 AT valenzuelapablodt isolationsequencingandphylogeneticanalysisofthehemagglutininneuraminidaseandnucleoproteingenesofthechileanequineinfluenzavirussubtypesh7n7andh3n8
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Isolation, sequencing and phylogenetic analysis of the hemagglutinin, neuraminidase and nucleoprotein genes of the Chilean equine influenza virus subtypes H7N7 and H3N8

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