Role of the phosphatase PP4 in the activation of JNK-1 in prostate carcinoma cell lines PC-3 and LNCaP resulting in increased AP-1 and EGR-1 activity

The specific signaling connections between the mitogen-activated protein kinases (MAPK) such as c-Jun N-terminal kinase (JNK-1) and phosphatases PP4 and M3/6, affecting the family of early nuclear factors, is complex and remains poorly understood. JNK-1 regulates cellular differentiation, apoptosis...

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Autores principales: INOSTROZA,JUAN, SÁENZ,LEONARDO, CALAF,GLORIA, CABELLO,GERTRUDIS, PARRA,EDUARDO
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2005
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602005000200006
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