Central actions of somatostatin in the generation and control of breathing
The neuropeptide somatostatin is involved in many functions in the central nervous system as well as in the periphery. When it is centrally injected, an irreversible apnea is often developed. In the present review, we discuss the effects of somatostatin as the result of its actions at three levels o...
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Sociedad de Biología de Chile
2005
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oai:scielo:S0716-976020050004000062006-04-18Central actions of somatostatin in the generation and control of breathingLlona,IsabelEugenín,Jaime apnea brainstem chemoreceptors respiratory rhythm The neuropeptide somatostatin is involved in many functions in the central nervous system as well as in the periphery. When it is centrally injected, an irreversible apnea is often developed. In the present review, we discuss the effects of somatostatin as the result of its actions at three levels of the respiratory neural network: a) by modulating the output of cranial or spinal motoneurons; b) by altering the genesis of the respiratory rhythm in the brainstem; and c) by regulating the chemosensory drive input into the respiratory pattern generatorinfo:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.38 n.4 20052005-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602005000400006en10.4067/S0716-97602005000400006 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
English |
topic |
apnea brainstem chemoreceptors respiratory rhythm |
spellingShingle |
apnea brainstem chemoreceptors respiratory rhythm Llona,Isabel Eugenín,Jaime Central actions of somatostatin in the generation and control of breathing |
description |
The neuropeptide somatostatin is involved in many functions in the central nervous system as well as in the periphery. When it is centrally injected, an irreversible apnea is often developed. In the present review, we discuss the effects of somatostatin as the result of its actions at three levels of the respiratory neural network: a) by modulating the output of cranial or spinal motoneurons; b) by altering the genesis of the respiratory rhythm in the brainstem; and c) by regulating the chemosensory drive input into the respiratory pattern generator |
author |
Llona,Isabel Eugenín,Jaime |
author_facet |
Llona,Isabel Eugenín,Jaime |
author_sort |
Llona,Isabel |
title |
Central actions of somatostatin in the generation and control of breathing |
title_short |
Central actions of somatostatin in the generation and control of breathing |
title_full |
Central actions of somatostatin in the generation and control of breathing |
title_fullStr |
Central actions of somatostatin in the generation and control of breathing |
title_full_unstemmed |
Central actions of somatostatin in the generation and control of breathing |
title_sort |
central actions of somatostatin in the generation and control of breathing |
publisher |
Sociedad de Biología de Chile |
publishDate |
2005 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602005000400006 |
work_keys_str_mv |
AT llonaisabel centralactionsofsomatostatininthegenerationandcontrolofbreathing AT eugeninjaime centralactionsofsomatostatininthegenerationandcontrolofbreathing |
_version_ |
1718441391755886592 |