Antioxidant activity of extract from Polygonum aviculare L.

Free radicals induce numerous diseases by lipid peroxidation, protein peroxidation, and DNA damage. It has been reported that numerous plant extracts have antioxidant activities to scavenge free radicals. Whether Polygonum aviculare L. (Polygonaceae) has antioxidant activity is unknown. In this stud...

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Autor principal:	HSU,CHIN-YUAN
Lenguaje:	English
Publicado:	Sociedad de Biología de Chile 2006
Materias:	antioxidant activity free radical phenolics lipid peroxidation DNA damage Polygonum aviculare L
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000200010
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spelling	oai:scielo:S0716-976020060002000102006-07-25Antioxidant activity of extract from Polygonum aviculare L.HSU,CHIN-YUAN antioxidant activity free radical phenolics lipid peroxidation DNA damage Polygonum aviculare L Free radicals induce numerous diseases by lipid peroxidation, protein peroxidation, and DNA damage. It has been reported that numerous plant extracts have antioxidant activities to scavenge free radicals. Whether Polygonum aviculare L. (Polygonaceae) has antioxidant activity is unknown. In this study, dried Polygonum aviculare L. was extracted by ethanol, and the extract was lyophilized. The antioxidant activities of extract powder were examined by free radical scavenging assays, superoxide radical scavenging assays, lipid peroxidation assays and hydroxyl radical-induced DNA strand scission assays. The results show that the IC50 value of Polygonum aviculare L. extract is 50 µg/ml in free radical scavenging assays, 0.8 µg/ml in superoxide radical scavenging assays, and 15 µg/ml in lipid peroxidation assays, respectively. Furthermore, Polygonum aviculare L. extract has DNA protective effect in hydroxyl radical-induced DNA strand scission assays. The total phenolics and flavonoid content of extract is 677.4 ± 62.7 µg/g and 112.7 ± 13 µg/g. The results indicate that Polygonum aviculare L. extract clearly has antioxidant effectsinfo:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.39 n.2 20062006-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000200010en10.4067/S0716-97602006000200010
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	antioxidant activity free radical phenolics lipid peroxidation DNA damage Polygonum aviculare L
spellingShingle	antioxidant activity free radical phenolics lipid peroxidation DNA damage Polygonum aviculare L HSU,CHIN-YUAN Antioxidant activity of extract from Polygonum aviculare L.
description	Free radicals induce numerous diseases by lipid peroxidation, protein peroxidation, and DNA damage. It has been reported that numerous plant extracts have antioxidant activities to scavenge free radicals. Whether Polygonum aviculare L. (Polygonaceae) has antioxidant activity is unknown. In this study, dried Polygonum aviculare L. was extracted by ethanol, and the extract was lyophilized. The antioxidant activities of extract powder were examined by free radical scavenging assays, superoxide radical scavenging assays, lipid peroxidation assays and hydroxyl radical-induced DNA strand scission assays. The results show that the IC50 value of Polygonum aviculare L. extract is 50 µg/ml in free radical scavenging assays, 0.8 µg/ml in superoxide radical scavenging assays, and 15 µg/ml in lipid peroxidation assays, respectively. Furthermore, Polygonum aviculare L. extract has DNA protective effect in hydroxyl radical-induced DNA strand scission assays. The total phenolics and flavonoid content of extract is 677.4 ± 62.7 µg/g and 112.7 ± 13 µg/g. The results indicate that Polygonum aviculare L. extract clearly has antioxidant effects
author	HSU,CHIN-YUAN
author_facet	HSU,CHIN-YUAN
author_sort	HSU,CHIN-YUAN
title	Antioxidant activity of extract from Polygonum aviculare L.
title_short	Antioxidant activity of extract from Polygonum aviculare L.
title_full	Antioxidant activity of extract from Polygonum aviculare L.
title_fullStr	Antioxidant activity of extract from Polygonum aviculare L.
title_full_unstemmed	Antioxidant activity of extract from Polygonum aviculare L.
title_sort	antioxidant activity of extract from polygonum aviculare l.
publisher	Sociedad de Biología de Chile
publishDate	2006
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602006000200010
work_keys_str_mv	AT hsuchinyuan antioxidantactivityofextractfrompolygonumavicularel
_version_	1718441401803341824

Antioxidant activity of extract from Polygonum aviculare L.

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