Influence of time at which oxytocin is administered during labor on uterine activity and perinatal death in pigs

Oxytocin is extensively used to induce or augment uterine contractions, especially to facilitate the third stage of labor in humans. Administration of oxytocin to parturient sows reduces duration of labor whereas mortality of the offspring may remain unchanged. This study aimed to evaluate whether t...

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Autores principales:	MOTA-ROJAS,DANIEL, VILLANUEVA-GARCÍA,DINA, VELAZQUEZ-ARMENTA,ELVIA Y, NAVA-OCAMPO,ALEJANDRO A, RAMÍREZ-NECOECHEA,RAMIRO, ALONSO-SPILSBURY,MARÍA, TRUJILLO,MARÍA E
Lenguaje:	English
Publicado:	Sociedad de Biología de Chile 2007
Materias:	Fetal distress Fetal monitoring Obstetric labor Oxytocin Uterine contractions
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602007000100006
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spelling	oai:scielo:S0716-976020070001000062007-11-15Influence of time at which oxytocin is administered during labor on uterine activity and perinatal death in pigsMOTA-ROJAS,DANIELVILLANUEVA-GARCÍA,DINAVELAZQUEZ-ARMENTA,ELVIA YNAVA-OCAMPO,ALEJANDRO ARAMÍREZ-NECOECHEA,RAMIROALONSO-SPILSBURY,MARÍATRUJILLO,MARÍA E Fetal distress Fetal monitoring Obstetric labor Oxytocin Uterine contractions Oxytocin is extensively used to induce or augment uterine contractions, especially to facilitate the third stage of labor in humans. Administration of oxytocin to parturient sows reduces duration of labor whereas mortality of the offspring may remain unchanged. This study aimed to evaluate whether time of administration of oxytocin during parturition may alter the uterine response and fetal outcomes. Two hundred parturient sows were randomly assigned to intramuscularly receive either saline solution (control group) or oxytocin 0.083 IU/kg immediately after the delivery of the 1st, 4th or 8th piglet (groups O-1, 0-4 and 0-8, respectively). Uterine effects and fetal outcomes were registered in all groups. The duration of labor was 20-40 min shorter (P < 0.0001) and time interval between babies was reduced by 3-5 min (P < 0.0001) in the three groups receiving oxytocin. The duration and intensity of contractions, meconium-stained piglets and intrapartum deaths decreased as time at which oxytocin administered during labor was increased. In group 0-8, we observed approximately 70% less meconium-stained piglets and intrapartum deaths than in the control group. In conclusion, oxytocin administered at early phases of parturition to sows may increase duration and intensity of uterine contractions as well as adverse fetal outcomesinfo:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.40 n.1 20072007-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602007000100006en10.4067/S0716-97602007000100006
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Fetal distress Fetal monitoring Obstetric labor Oxytocin Uterine contractions
spellingShingle	Fetal distress Fetal monitoring Obstetric labor Oxytocin Uterine contractions MOTA-ROJAS,DANIEL VILLANUEVA-GARCÍA,DINA VELAZQUEZ-ARMENTA,ELVIA Y NAVA-OCAMPO,ALEJANDRO A RAMÍREZ-NECOECHEA,RAMIRO ALONSO-SPILSBURY,MARÍA TRUJILLO,MARÍA E Influence of time at which oxytocin is administered during labor on uterine activity and perinatal death in pigs
description	Oxytocin is extensively used to induce or augment uterine contractions, especially to facilitate the third stage of labor in humans. Administration of oxytocin to parturient sows reduces duration of labor whereas mortality of the offspring may remain unchanged. This study aimed to evaluate whether time of administration of oxytocin during parturition may alter the uterine response and fetal outcomes. Two hundred parturient sows were randomly assigned to intramuscularly receive either saline solution (control group) or oxytocin 0.083 IU/kg immediately after the delivery of the 1st, 4th or 8th piglet (groups O-1, 0-4 and 0-8, respectively). Uterine effects and fetal outcomes were registered in all groups. The duration of labor was 20-40 min shorter (P < 0.0001) and time interval between babies was reduced by 3-5 min (P < 0.0001) in the three groups receiving oxytocin. The duration and intensity of contractions, meconium-stained piglets and intrapartum deaths decreased as time at which oxytocin administered during labor was increased. In group 0-8, we observed approximately 70% less meconium-stained piglets and intrapartum deaths than in the control group. In conclusion, oxytocin administered at early phases of parturition to sows may increase duration and intensity of uterine contractions as well as adverse fetal outcomes
author	MOTA-ROJAS,DANIEL VILLANUEVA-GARCÍA,DINA VELAZQUEZ-ARMENTA,ELVIA Y NAVA-OCAMPO,ALEJANDRO A RAMÍREZ-NECOECHEA,RAMIRO ALONSO-SPILSBURY,MARÍA TRUJILLO,MARÍA E
author_facet	MOTA-ROJAS,DANIEL VILLANUEVA-GARCÍA,DINA VELAZQUEZ-ARMENTA,ELVIA Y NAVA-OCAMPO,ALEJANDRO A RAMÍREZ-NECOECHEA,RAMIRO ALONSO-SPILSBURY,MARÍA TRUJILLO,MARÍA E
author_sort	MOTA-ROJAS,DANIEL
title	Influence of time at which oxytocin is administered during labor on uterine activity and perinatal death in pigs
title_short	Influence of time at which oxytocin is administered during labor on uterine activity and perinatal death in pigs
title_full	Influence of time at which oxytocin is administered during labor on uterine activity and perinatal death in pigs
title_fullStr	Influence of time at which oxytocin is administered during labor on uterine activity and perinatal death in pigs
title_full_unstemmed	Influence of time at which oxytocin is administered during labor on uterine activity and perinatal death in pigs
title_sort	influence of time at which oxytocin is administered during labor on uterine activity and perinatal death in pigs
publisher	Sociedad de Biología de Chile
publishDate	2007
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602007000100006
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Influence of time at which oxytocin is administered during labor on uterine activity and perinatal death in pigs

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