The ingestión of a Nectandra membranácea extract changes the bioavailability of technetium-99m radiobiocomplex in rat organs
The radiobiocomplexes labeled with technetium-99m (Tc-99m) have been widely used in nuclear medicine in single photon emission computed tomography and in basic research. The aim of this study was to assess the influence of a Nectandra membranácea extract on the bioavailability of the sodium pertechn...
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Sociedad de Biología de Chile
2007
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oai:scielo:S0716-976020070002000042008-06-13The ingestión of a Nectandra membranácea extract changes the bioavailability of technetium-99m radiobiocomplex in rat organsRAMOS FARÍAS MORENO,SILVANAARNOBIO,ADRIANOCARVALH0,JORGE JOSÉ DENASCIMENT0,LUCIAOLIVEIRA TIMOTEO,MARGARETHOLEJ,BENIKAZAN ROCHA,EMELYPEREIRA,MARIOBERNARDO-FILH0,MARIOQUERINO DE ARAÚJO CALDAS,LUIZ Nectandra membranácea bioavailability sodium pertechnetate radiobiocomplex The radiobiocomplexes labeled with technetium-99m (Tc-99m) have been widely used in nuclear medicine in single photon emission computed tomography and in basic research. The aim of this study was to assess the influence of a Nectandra membranácea extract on the bioavailability of the sodium pertechnetate (Na99mTc0(4)) radiobiocomplex in rat organs. The animals were treated with a N. membranácea extract (30 mg/ ml), for 6 days. Na99mTc0(4) was injected, the organs were isolated and weighed, and the radioactivity was determined in each organ (%ATI/organ). The %ATI/organ was divided by the mass of each organ to calculate the %ATI/g. A significant increase of the %ATI/organ of Na99mTc0(4) was observed in muscle and thyroid as well as in the %ATI/g in the heart, kidney and thyroid. These findings could result from the interaction between components of the plant extract and the radiobiocomplex which may influence the uptake Na99mTc0(4) in rat organs. Therefore, precaution is suggested in the interpretation of nuclear medicine results in patients using this herbinfo:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.40 n.2 20072007-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602007000200004en10.4067/S0716-97602007000200004 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
English |
| topic |
Nectandra membranácea bioavailability sodium pertechnetate radiobiocomplex |
| spellingShingle |
Nectandra membranácea bioavailability sodium pertechnetate radiobiocomplex RAMOS FARÍAS MORENO,SILVANA ARNOBIO,ADRIANO CARVALH0,JORGE JOSÉ DE NASCIMENT0,LUCIA OLIVEIRA TIMOTEO,MARGARETH OLEJ,BENI KAZAN ROCHA,EMELY PEREIRA,MARIO BERNARDO-FILH0,MARIO QUERINO DE ARAÚJO CALDAS,LUIZ The ingestión of a Nectandra membranácea extract changes the bioavailability of technetium-99m radiobiocomplex in rat organs |
| description |
The radiobiocomplexes labeled with technetium-99m (Tc-99m) have been widely used in nuclear medicine in single photon emission computed tomography and in basic research. The aim of this study was to assess the influence of a Nectandra membranácea extract on the bioavailability of the sodium pertechnetate (Na99mTc0(4)) radiobiocomplex in rat organs. The animals were treated with a N. membranácea extract (30 mg/ ml), for 6 days. Na99mTc0(4) was injected, the organs were isolated and weighed, and the radioactivity was determined in each organ (%ATI/organ). The %ATI/organ was divided by the mass of each organ to calculate the %ATI/g. A significant increase of the %ATI/organ of Na99mTc0(4) was observed in muscle and thyroid as well as in the %ATI/g in the heart, kidney and thyroid. These findings could result from the interaction between components of the plant extract and the radiobiocomplex which may influence the uptake Na99mTc0(4) in rat organs. Therefore, precaution is suggested in the interpretation of nuclear medicine results in patients using this herb |
| author |
RAMOS FARÍAS MORENO,SILVANA ARNOBIO,ADRIANO CARVALH0,JORGE JOSÉ DE NASCIMENT0,LUCIA OLIVEIRA TIMOTEO,MARGARETH OLEJ,BENI KAZAN ROCHA,EMELY PEREIRA,MARIO BERNARDO-FILH0,MARIO QUERINO DE ARAÚJO CALDAS,LUIZ |
| author_facet |
RAMOS FARÍAS MORENO,SILVANA ARNOBIO,ADRIANO CARVALH0,JORGE JOSÉ DE NASCIMENT0,LUCIA OLIVEIRA TIMOTEO,MARGARETH OLEJ,BENI KAZAN ROCHA,EMELY PEREIRA,MARIO BERNARDO-FILH0,MARIO QUERINO DE ARAÚJO CALDAS,LUIZ |
| author_sort |
RAMOS FARÍAS MORENO,SILVANA |
| title |
The ingestión of a Nectandra membranácea extract changes the bioavailability of technetium-99m radiobiocomplex in rat organs |
| title_short |
The ingestión of a Nectandra membranácea extract changes the bioavailability of technetium-99m radiobiocomplex in rat organs |
| title_full |
The ingestión of a Nectandra membranácea extract changes the bioavailability of technetium-99m radiobiocomplex in rat organs |
| title_fullStr |
The ingestión of a Nectandra membranácea extract changes the bioavailability of technetium-99m radiobiocomplex in rat organs |
| title_full_unstemmed |
The ingestión of a Nectandra membranácea extract changes the bioavailability of technetium-99m radiobiocomplex in rat organs |
| title_sort |
ingestión of a nectandra membranácea extract changes the bioavailability of technetium-99m radiobiocomplex in rat organs |
| publisher |
Sociedad de Biología de Chile |
| publishDate |
2007 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602007000200004 |
| work_keys_str_mv |
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| _version_ |
1718441415054196736 |