Construction of an immunotoxin by linking a monoclonal antibody against the human epidermal growth factor receptor and a hemolytic toxin

Hybrid molecules obtained through conjugation of monoclonal antibodies and toxins constitute an approach under exploration to generate potential agents for the treatment of cancer and other diseases. A frequently employed toxic component in the construction of such immunotoxins is ricin, a plant tox...

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Autores principales: AVILA,ANA D, CALDERÓN,CARLOS F, PEREZ,RITA M, PONS,CARMEN, PEREDA,CELIA M, ORTIZ,ANA R
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2007
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602007000200008
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