Antagonism of morphine-induced central respiratory depression by donepezil in the anesthetized rabbit

Morphine is often used in cancer pain and postoperative analgesic management but induces respiratory depression. Therefore, there is an ongoing search for drug candidates that can antagonize morphine-induced respiratory depression but have no effect on morphine-induced analgesia. Acetylcholine is an...

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Autores principales: TSUJITA,MIKI, SAKURABA,SHIGEKI, KURIBAYASHI,JUNYA, HOSOKAWA,YUKI, HATORI,EIKI, OKADA,YASUMASA, KASHIWAGI,MASANORI, TAKEDA,JUNZO, KUWANA,SHUN-ICHI
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2007
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602007000400008
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