High frequency of p 16 promoter methylation in non-small cell lung carcinomas from Chile

The inactivation of tumour suppressor genes by aberrant methylation of promoter regions has been described as a frequent event in neoplasia development, including lung cancer. The p16 gene is a tumour suppressor gene involved in the regulation of cell cycle progression that has been reported to be i...

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Autores principales: GUZMAN,LEDA M, KORIYAMA,CHIHAYA, AKIBA,SUMINORI, EIZURU,YOSHITO, CASTILLO,DARWINS, CORVALAN,ALEJANDRO, AGUAYO,FRANCISCO R
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2007
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602007000400011
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