Study of Cytochrome P450 2E1 and its allele Variants in Liver Injury of Nondiabetic, Nonalcoholic Steatohepatitis Obese Women

Study of Cytochrome P450 2E1 and its allele Variants in Liver Injury of Nondiabetic, Nonalcoholic Steatohepatitis Obese Women

CYP2E1 enzyme is related to nonalcoholic steatohepatitis (NASH) due to its ability for reactive oxygen species production, which can be influenced by polymorphisms in the gene. The aim of this study was to investigate hepatic levels, activity, and polymorphisms of the CYP2E1 gene to correlate it wit...

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Autores principales: VARELA,NELSON M, QUIÑONES,LUIS A, ORELLANA,MYRIAM, PONIACHIK,JAIME, CSENDES,ATTILA, SMOK,GLADYS, RODRIGO,RAMÓN, CÁCERES,DANTE D, VIDELA,LUIS A
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2008
Materias:
steatohepatitis
NASH
CYP2E1
obesity
genotype
chlorzoxazone
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000100010
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