Friend erythroleukemia cells induce angiogenesis in chick embryo chorioallantoic membrane and in human umbilical vein endothelial cells

The effects of Friend erythroleukemia cells on angiogenesis were studied in chick embryo chorioallantoic membrane assay and in human umbilical vein endothelial cells. In chorioallantoic membrane assay, the conditioned medium of Friend cells stimulated in vivo angiogenesis to an extent comparable to...

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Autores principales:	PACINI,STEFANIA, PUNZI,TIZIANA, GULISANO,MASSIMO, RUGGIERO,MARCO
Lenguaje:	English
Publicado:	Sociedad de Biología de Chile 2008
Materias:	angiogenesis chick embryo chorioallantoic membrane assay Friend erythroleukemia human endothelial cells
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000100012
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spelling	oai:scielo:S0716-976020080001000122008-08-21Friend erythroleukemia cells induce angiogenesis in chick embryo chorioallantoic membrane and in human umbilical vein endothelial cellsPACINI,STEFANIAPUNZI,TIZIANAGULISANO,MASSIMORUGGIERO,MARCO angiogenesis chick embryo chorioallantoic membrane assay Friend erythroleukemia human endothelial cells The effects of Friend erythroleukemia cells on angiogenesis were studied in chick embryo chorioallantoic membrane assay and in human umbilical vein endothelial cells. In chorioallantoic membrane assay, the conditioned medium of Friend cells stimulated in vivo angiogenesis to an extent comparable to that observed with Prostaglandin El, used as positive control. Prostaglandin El added to conditioned medium of Friend cells did not further increase angiogenesis. Conditioned medium of Friend erythroleukemia cells also stimulated proliferation of human umbilical vein endothelial cells to an extent comparable to that observed with fetal bovine serum, used as positive control. Conditioned medium and fetal bovine serum together did not affect human umbilical vein endothelial cells proliferation, as compared to that observed when tested separately. These results seem to indicate that Friend erythroleukemia cells produce and secrete factors stimulating angiogenesis. These findings extend and confirm the hypothesis that successful angiogenesis is necessary for development of leukemiasinfo:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.41 n.1 20082008-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000100012en10.4067/S0716-97602008000100012
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	angiogenesis chick embryo chorioallantoic membrane assay Friend erythroleukemia human endothelial cells
spellingShingle	angiogenesis chick embryo chorioallantoic membrane assay Friend erythroleukemia human endothelial cells PACINI,STEFANIA PUNZI,TIZIANA GULISANO,MASSIMO RUGGIERO,MARCO Friend erythroleukemia cells induce angiogenesis in chick embryo chorioallantoic membrane and in human umbilical vein endothelial cells
description	The effects of Friend erythroleukemia cells on angiogenesis were studied in chick embryo chorioallantoic membrane assay and in human umbilical vein endothelial cells. In chorioallantoic membrane assay, the conditioned medium of Friend cells stimulated in vivo angiogenesis to an extent comparable to that observed with Prostaglandin El, used as positive control. Prostaglandin El added to conditioned medium of Friend cells did not further increase angiogenesis. Conditioned medium of Friend erythroleukemia cells also stimulated proliferation of human umbilical vein endothelial cells to an extent comparable to that observed with fetal bovine serum, used as positive control. Conditioned medium and fetal bovine serum together did not affect human umbilical vein endothelial cells proliferation, as compared to that observed when tested separately. These results seem to indicate that Friend erythroleukemia cells produce and secrete factors stimulating angiogenesis. These findings extend and confirm the hypothesis that successful angiogenesis is necessary for development of leukemias
author	PACINI,STEFANIA PUNZI,TIZIANA GULISANO,MASSIMO RUGGIERO,MARCO
author_facet	PACINI,STEFANIA PUNZI,TIZIANA GULISANO,MASSIMO RUGGIERO,MARCO
author_sort	PACINI,STEFANIA
title	Friend erythroleukemia cells induce angiogenesis in chick embryo chorioallantoic membrane and in human umbilical vein endothelial cells
title_short	Friend erythroleukemia cells induce angiogenesis in chick embryo chorioallantoic membrane and in human umbilical vein endothelial cells
title_full	Friend erythroleukemia cells induce angiogenesis in chick embryo chorioallantoic membrane and in human umbilical vein endothelial cells
title_fullStr	Friend erythroleukemia cells induce angiogenesis in chick embryo chorioallantoic membrane and in human umbilical vein endothelial cells
title_full_unstemmed	Friend erythroleukemia cells induce angiogenesis in chick embryo chorioallantoic membrane and in human umbilical vein endothelial cells
title_sort	friend erythroleukemia cells induce angiogenesis in chick embryo chorioallantoic membrane and in human umbilical vein endothelial cells
publisher	Sociedad de Biología de Chile
publishDate	2008
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000100012
work_keys_str_mv	AT pacinistefania frienderythroleukemiacellsinduceangiogenesisinchickembryochorioallantoicmembraneandinhumanumbilicalveinendothelialcells AT punzitiziana frienderythroleukemiacellsinduceangiogenesisinchickembryochorioallantoicmembraneandinhumanumbilicalveinendothelialcells AT gulisanomassimo frienderythroleukemiacellsinduceangiogenesisinchickembryochorioallantoicmembraneandinhumanumbilicalveinendothelialcells AT ruggieromarco frienderythroleukemiacellsinduceangiogenesisinchickembryochorioallantoicmembraneandinhumanumbilicalveinendothelialcells
_version_	1718441430314123264

Friend erythroleukemia cells induce angiogenesis in chick embryo chorioallantoic membrane and in human umbilical vein endothelial cells

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