Small-molecule aggregation inhibitors reduce excess amyloid in a trisomy 16 mouse cortical cell line
We have previously characterized a number of small molecule organic compounds that prevent the aggregation of the β-amyloid peptide and its neurotoxicity in hippocampal neuronal cultures. We have now evaluated the effects of such compounds on amyloid precursor protein (APP) accumulation in...
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| Auteurs principaux: | , , , , , , |
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| Langue: | English |
| Publié: |
Sociedad de Biología de Chile
2008
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| Accès en ligne: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000200001 |
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