Antioxidant activity of 50% aqueous - ethanol extract from Acantholippia deserticola

The antioxidant properties oí Acantholippia deserticola, a herb used in traditional northern Chilean medicine was studied using free radical - generating systems. The 50% aqueous - ethanol extract oí Acantholippia deserticola protected against non-enzymatic lipid peroxidation in microsomal membranes...

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Autores principales: MORALES,GLAUCO, PAREDES,ADRIÁN, SIERRA,PATRICIA, LOYOLA,LUIS A
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2008
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000200004
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spelling oai:scielo:S0716-976020080002000042009-03-24Antioxidant activity of 50% aqueous - ethanol extract from Acantholippia deserticolaMORALES,GLAUCOPAREDES,ADRIÁNSIERRA,PATRICIALOYOLA,LUIS A Acantholippia deserticola northern Chilean medicinal plant phenolics free radicáis scavenging microsomal lipid peroxidation The antioxidant properties oí Acantholippia deserticola, a herb used in traditional northern Chilean medicine was studied using free radical - generating systems. The 50% aqueous - ethanol extract oí Acantholippia deserticola protected against non-enzymatic lipid peroxidation in microsomal membranes of rat, induced by an Fe++ - ascorbate system and measured spectrophotometrically by the TBARS test, and had strong free radical scavenging capacities on stable ABTS and DPPH radicáis. The results shows that the IC50 valué of the 50% aqueous - ethanolic extract oí A.deserticola is 18 ± 0.5 μg/mL in DPPH radical - scavenging, 15 ± 0.8 μg/mL in lipid peroxidation , Total Antioxidant Activity (TAA) is 0.95 mM of Trolox per mg/mL of extract. The total phenolics content of extract is 725 ± 12 mg of gallic acid equivalent per g of dried extract. The results indicate that the 50% aqueous - ethanol extract oí Acantholippia deserticola clearly has antioxidant properties.info:eu-repo/semantics/openAccessSociedad de Biología de ChileBiological Research v.41 n.2 20082008-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000200004en10.4067/S0716-97602008000200004
institution Scielo Chile
collection Scielo Chile
language English
topic Acantholippia deserticola
northern Chilean medicinal plant
phenolics
free radicáis scavenging
microsomal lipid peroxidation
spellingShingle Acantholippia deserticola
northern Chilean medicinal plant
phenolics
free radicáis scavenging
microsomal lipid peroxidation
MORALES,GLAUCO
PAREDES,ADRIÁN
SIERRA,PATRICIA
LOYOLA,LUIS A
Antioxidant activity of 50% aqueous - ethanol extract from Acantholippia deserticola
description The antioxidant properties oí Acantholippia deserticola, a herb used in traditional northern Chilean medicine was studied using free radical - generating systems. The 50% aqueous - ethanol extract oí Acantholippia deserticola protected against non-enzymatic lipid peroxidation in microsomal membranes of rat, induced by an Fe++ - ascorbate system and measured spectrophotometrically by the TBARS test, and had strong free radical scavenging capacities on stable ABTS and DPPH radicáis. The results shows that the IC50 valué of the 50% aqueous - ethanolic extract oí A.deserticola is 18 ± 0.5 μg/mL in DPPH radical - scavenging, 15 ± 0.8 μg/mL in lipid peroxidation , Total Antioxidant Activity (TAA) is 0.95 mM of Trolox per mg/mL of extract. The total phenolics content of extract is 725 ± 12 mg of gallic acid equivalent per g of dried extract. The results indicate that the 50% aqueous - ethanol extract oí Acantholippia deserticola clearly has antioxidant properties.
author MORALES,GLAUCO
PAREDES,ADRIÁN
SIERRA,PATRICIA
LOYOLA,LUIS A
author_facet MORALES,GLAUCO
PAREDES,ADRIÁN
SIERRA,PATRICIA
LOYOLA,LUIS A
author_sort MORALES,GLAUCO
title Antioxidant activity of 50% aqueous - ethanol extract from Acantholippia deserticola
title_short Antioxidant activity of 50% aqueous - ethanol extract from Acantholippia deserticola
title_full Antioxidant activity of 50% aqueous - ethanol extract from Acantholippia deserticola
title_fullStr Antioxidant activity of 50% aqueous - ethanol extract from Acantholippia deserticola
title_full_unstemmed Antioxidant activity of 50% aqueous - ethanol extract from Acantholippia deserticola
title_sort antioxidant activity of 50% aqueous - ethanol extract from acantholippia deserticola
publisher Sociedad de Biología de Chile
publishDate 2008
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000200004
work_keys_str_mv AT moralesglauco antioxidantactivityof50aqueousethanolextractfromacantholippiadeserticola
AT paredesadrian antioxidantactivityof50aqueousethanolextractfromacantholippiadeserticola
AT sierrapatricia antioxidantactivityof50aqueousethanolextractfromacantholippiadeserticola
AT loyolaluisa antioxidantactivityof50aqueousethanolextractfromacantholippiadeserticola
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