Microtubule proteins and their post-translational forms in the cerebrospinal fluid of patients with paraparesis associated with HTLV-I infection and in SH-SY5Y cells: An in vitro model of HTLV-I-induced disease

Microtubule proteins and their post-translational forms in the cerebrospinal fluid of patients with paraparesis associated with HTLV-I infection and in SH-SY5Y cells: An in vitro model of HTLV-I-induced disease

HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is characterized by axonal degeneration of the corticospinal tracts. The specific requirements for transport of proteins and organelles to the distal part of the long axon are crucial in the corticospinal tracts. Microtubule dysfunc...

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Autores principales: MALDONADO,HORACIO, ORTIZ-RIAÑO,EMILIO, KRAUSE,BERNARDO, BARRIGA,ANDRÉS, MEDINA,FERNANDO, PANDO,M ELSA, ALBERTI,CAROLINA, KETTLUN,ANA M, COLLADOS,LUCÍA, GARCÍA,LORENA, CARTIER,LUIS, VALENZUELA,M ANTONIETA
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2008
Materias:
Tropical spastic paraparesis
cerebrospinal fluid
SH-SY5Y cells
retraction
tau
phosphorylated-tau forms
tubulin
acetyl-tubulin
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000300001
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