DNA methylation profile in diffuse type gastric cancer: evidence for hypermethylation of the BRCA1 promoter region in early-onset gastric carcinogenesis

DNA methylation profile in diffuse type gastric cancer: evidence for hypermethylation of the BRCA1 promoter region in early-onset gastric carcinogenesis

Diffuse type gastric carcinoma is the most aggressive type of gastric cáncer. This type of tumor is not preceded by precancerous changes and is associated with early-onset and hereditary syndromes. To test the hypothesis that DNA methylation profile would be useful for molecular classification of th...

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Autores principales: BERNAL,CAROLINA, VARGAS,MACARENA, OSSANDÓN,FRANCISCO, SANTIBÁÑEZ,EUDOCIA, URRUTIA,JULIO, LUENGO,VÍCTOR, ZAVALA,LUIS F, BACKHOUSE,CLAUDIA, PALMA,MARIANA, ARGANDOÑA,JORGE, AGUAYO,FRANCISCO, CORVALÁN,ALEJANDRO
Lenguaje:English
Publicado: Sociedad de Biología de Chile 2008
Materias:
gastric cáncer
diffuse type
early-onset
BRCA-1
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602008000300007
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